Methyltrienolone
Modify Date: 2026-07-01 21:24:37
Methyltrienolone structure
|
Common Name | Methyltrienolone | ||
|---|---|---|---|---|
| CAS Number | 965-93-5 | Molecular Weight | 284.393 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 485.9±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H24O2 | Melting Point | 206-209 °C | |
| MSDS | Chinese USA | Flash Point | 206.3±21.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of MethyltrienoloneAn orally active anabolic-androgenic steroid and a 19-nortestosterone derivative that has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.. |
| Name | 17β-hydroxy-17-methylestra-4,9,11-trien-3-one |
|---|---|
| Synonym | More Synonyms |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 485.9±45.0 °C at 760 mmHg |
| Melting Point | 206-209 °C |
| Molecular Formula | C19H24O2 |
| Molecular Weight | 284.393 |
| Flash Point | 206.3±21.3 °C |
| Exact Mass | 284.177643 |
| PSA | 37.30000 |
| LogP | 2.81 |
| Vapour density | 5.31 (vs air) |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.597 |
| InChIKey | CCCIJQPRIXGQOE-XWSJACJDSA-N |
| SMILES | CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C=CC21C |
| Storage condition | 2-8°C |
| Water Solubility | INSOLUBLE |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | F,Xi |
| Risk Phrases | R11:Highly Flammable. R43:May cause sensitization by skin contact. |
| Safety Phrases | S16-S36/37 |
| RIDADR | UN 1312 4.1/PG 3 |
| WGK Germany | 2 |
| RTECS | DT5095000 |
| Packaging Group | III |
| Hazard Class | 4.1 |
| HS Code | 29061900 |
| HS Code | 29061900 |
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Bisphenol A affects androgen receptor function via multiple mechanisms
Chem. Biol. Interact. 203(3) , 556-64, (2013) • BPA antagonizes AR function by competitive inhibition of androgen binding. • Prevents functional foci formation in the nucleus. • Reduce the AR presence in the nucleus. • BPAF have similar activatio... |
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Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice.
Oncotarget 6(8) , 6136-50, (2015) There is a critical need for therapeutic agents that can target the amino-terminal domain (NTD) of androgen receptor (AR) for the treatment of castration-resistant prostate cancer (CRPC). Calmodulin (... |
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The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.
Oncotarget 5(6) , 1666-82, (2014) Prostate cancer (PCa) is among the leading causes of cancer-related death in men. Androgen receptor (AR) signaling plays a seminal role in prostate development and homeostasis, and dysregulation of th... |
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Name: Relative binding affinity for androgen receptor in rat prostate cytosol extract compa...
Source: ChEMBL
Target: Androgen receptor
External Id: CHEMBL648260
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Name: Nonspecific binding (NSB) (R1881 = 1.00) calculated using an empirically derived rela...
Source: ChEMBL
Target: N/A
External Id: CHEMBL844867
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Name: Binding selectivity index (BSI) as ratio of RBA for androgen receptor to non-specific...
Source: ChEMBL
Target: Androgen receptor
External Id: CHEMBL844269
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Name: Thermal Shift Assay. Domain start/stop: M626-G740
Source: ChEMBL
Target: Peregrin
External Id: CHEMBL4650107
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Name: Thermal Shift Assay. Domain: start/stop: M1-L298
Source: ChEMBL
Target: Cyclin-dependent kinase 2
External Id: CHEMBL5062802
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Name: Maximum binding of [3H]R-1881 to human androgen receptor at 283 K
Source: ChEMBL
Target: Androgen receptor
External Id: CHEMBL839989
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Name: Binding affinity to androgen receptor by fluorescence binding assay
Source: ChEMBL
Target: Androgen receptor
External Id: CHEMBL1291059
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Name: Maximum binding of [3H]-R-1881 to human androgen receptor at 278 K
Source: ChEMBL
Target: Androgen receptor
External Id: CHEMBL839988
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Name: Maximum binding of [3H]R-1881 to human androgen receptor at 273 K
Source: ChEMBL
Target: Androgen receptor
External Id: CHEMBL839987
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Name: Relative binding affinity against glucocorticoid receptor in rat liver cytosol extrac...
Source: ChEMBL
Target: Glucocorticoid receptor
External Id: CHEMBL685136
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| 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one |
| 17a-Methyl-3-oxo-4,9,11-estratrien-17b-ol |
| 17α-Methyl-17β-hydroxyestra-4,9(10),11-trien-3-one |
| Methyltrienolone |
| (17β)-17-hydroxy-17-methyl-estra-4,9,11-triene-3-one |
| (17b)-17-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| 17-β-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| 17α-Methyltrienolone |
| 17α-Methyl-17β-hydroxyestra-4,9,11-trien-3-one |
| 17-β-hydroxy-17-methylestra-4,9,11-trien-3-one (9CI) |
| 3-Oxo-17β-hydroxy-17α-methylestra-4,9,11-triene |
| 17A-METHYL-TRENBOLONE |
| (17b)-17-Hydroxy-17-methyl-estra-4,9,11-trien-3-one |
| 17a-Methyl-4,9,11-estratrien-17b-ol-3-one |
| 3-Oxo-17b-hydroxy-17-methylestra-4,9,11-triene |
| 17α-Methyl-3-oxo-4,9,11-estratrien-17β-ol |
| 17a-Methyl-17b-hydroxyestra-4,9(10),11-trien-3-one |
| 17b-Hydroxy-17-methyl-19-norandrosta-4,9,11-trien-3-one |
| 17-β-hydroxy-17-methyl-19-norandrosta-4,9,11-triene-3-one |
| 17β-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| Methyl trenbolone(Metribolone) |
| MFCD00199021 |
| R1881 |
| 3-Oxo-17b-hydroxy-17a-methylestra-4,9,11-triene |
| 17a-Methyltrienolone |
| 17a-Methyl-17b-hydroxyestra-4,9,11-trien-3-one |
| 17b-Hydroxy-17-methylestra-4,9,11-trien-3-one |
| 3-Oxo-17β-hydroxy-17-methylestra-4,9,11-triene |
| RU-1881 |
| Metribolone |
| (17β)-17-Hydroxy-17-methylestra-4,9,11-trien-3-one |