4-Chloro-p-fluorobutyrophenone

4-Chloro-p-fluorobutyrophenone Structure
4-Chloro-p-fluorobutyrophenone structure
Common Name 4-Chloro-p-fluorobutyrophenone
CAS Number 3874-54-2 Molecular Weight 200.637
Density 1.2±0.1 g/cm3 Boiling Point 299.1±20.0 °C at 760 mmHg
Molecular Formula C10H10ClFO Melting Point 5-6 °C
MSDS USA Flash Point 134.7±21.8 °C

Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one.

Bioorg. Med. Chem. 16 , 7291-301, (2008)

The synthesis and exploration of novel butyrophenones have led to the identification of a diazepane analogue of haloperidol, 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one (compound 13) with an interesting multireceptor binding profile...