Metacycline hydrochloride

Metacycline hydrochloride Structure
Metacycline hydrochloride structure
Common Name Metacycline hydrochloride
CAS Number 3963-95-9 Molecular Weight 478.880
Density N/A Boiling Point 813.8ºC at 760 mmHg
Molecular Formula C22H23ClN2O8 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Overlapping and asymmetric functions of TCR signaling during thymic selection of CD4 and CD8 lineages.

J. Immunol. 192(11) , 5151-9, (2014)

TCR signaling plays a central role in directing developmental fates of thymocytes. Current models suggest TCR signal duration directs CD4 versus CD8 lineage development. To investigate the role of TCR signaling during positive selection directly, we switched ...

Improvements in europium sensitized fluorimetric determination of demeclocycline and methacycline.

J. Pharm. Biomed. Anal. 37(5) , 1101-4, (2005)

Demeclocycline (DM) and methacycline (MT) have been determined by europium-sensitized fluorescence, using EDTA as co-ligand and cetyltrimethylammonium chloride as surfactant. The methods have been developed in slightly alkaline solutions, with the formation o...

Simple continuous and simultaneous determination of tetracycline residues.

Res. Vet. Sci. 56(3) , 277-83, (1994)

A new continuous separation method was developed for the determination of five different tetracyclines (oxytetracycline, tetracycline, chlortetracycline, methacycline and doxycycline). A bioassay using minimum medium (MM) seeded with Bacillus subtilis ATCC 66...

The extra-weak chemiluminescence generated during oxidation of some tetracycline antibiotics. 1. Autoxidation.

J. Photochem. Photobiol. B, Biol. 14(4) , 329-43, (1992)

Chemiluminescence (CL) appearing during autoxidation of tetracycline (TC) antibiotics has been studied. The CL spectrum consists of four emission bands with maxima at 520, 585, 640 and 700 nm. The bands at 585, 640 and 700 nm are similar to those observed for...

Optical properties of metacycline, oxytetracycline and chlortetracycline europium complexes in the presence of hydrogen peroxide.

J. Fluoresc. 19(4) , 715-21, (2009)

Tetracycline possesses a great tendency to form complexes with a number of chemical species, particularly with Eu3+ ions. In this work we investigate the europium optical properties of three tetracyclines europium complexes: Metacycline (MTc), Oxytetracycline...

Quantitative analysis of methacycline hydrochloride by direct potentiometry using the internal solid contact sensor.

Anal. Sci. 23(2) , 231-3, (2007)

An internal solid contact sensor (ISCS) for the determination of methacycline hydrochloride (MC.Cl), Pt/PPy/PVC(MC-PT), is described, based on the use of conducting poly(pyrrole) (PPy) as solid contact material and MC-phosphotungstate (PT) as the ion exchange...

Lysozyme-enhanced europium(III)-metacycline luminescence and its application to the determination of metacycline.

Anal. Sci. 21(5) , 541-4, (2005)

A new spectrofluorometric method is described for the determination of metacycline (MC), based on modified enzyme-amplified lanthanide luminescence. Under the optimum conditions, Eu3+-MC forms a ternary complex with lysozyme in close proximity. Then lysozyme ...

[Determination of metacycline in mixture sample by synchronous-derivative fluorimetry].

Guang Pu Xue Yu Guang Pu Fen Xi 26(8) , 1530-2, (2006)

A new synchronous-derivative fluorimetric method for the determination of metacycline (MTC) in the presence of oxytetracycline (OTC) is proposed. The degradation products of MTC in 0.1 mol x L(-1) NaOH are strongly fluorescent. The addition of cetyltrimethyla...

Isolation of doxycycline, 6-epidoxycycline and 2-acetyl-2- decarboxamidometacycline from commercial metacycline by preparative column liquid chromatography on silica gel.

J. Chromatogr. A. 586(1) , 67-72, (1991)

Isolation of doxycycline, 6-epidoxycycline and 2-acetyl-2-decaboxamidometacycline from commercial metacycline was achieved by preparative column liquid chromatography on silica gel, previously impregnated with edetate (EDTA). Careful control of the pH of EDTA...

Determination of metacycline and related substances by column liquid chromatography on poly(styrene-divinylbenzene).

J. Chromatogr. A. 586(1) , 61-6, (1991)

Isocratic column liquid chromatography on poly(styrene-divinylbenzene) copolymer allowed complete separation of metacycline, 4-epimetacycline, oxytetracycline, doxycycline and 6-epidoxycycline. 2-Acetyl-2-decarboxamidometacycline was eluted on the tail of met...