7-Aminoheptanoic acid

7-Aminoheptanoic acid Structure
7-Aminoheptanoic acid structure
Common Name 7-Aminoheptanoic acid
CAS Number 929-17-9 Molecular Weight 145.199
Density 1.0±0.1 g/cm3 Boiling Point 270.6±23.0 °C at 760 mmHg
Molecular Formula C7H15NO2 Melting Point 192-195 °C(lit.)
MSDS Chinese USA Flash Point 117.5±22.6 °C

Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.

Eur. J. Med. Chem. 46 , 1483-98, (2011)

A new series of potential GABA uptake inhibitors starting from of 1H-imidazol-4-ylacetic acid with the carboxylic acid side chain originating from different positions and varying in length have been synthesized and tested for the inhibitory potency at the fou...

Surface interactions of a homologous series of alpha,omega-amino acids on colloidal silver and gold.

Biospectroscopy 5(1) , 9-17, (1999)

Surface enhanced Raman spectroscopy (SERS) was used to characterize a homologous series of alpha,omega-amino acids on colloidal gold and silver. Raman and SER spectra of the alpha,omega-amino acids, NH2(CH2)nCOOH (n = 3-7), are presented and analyzed, reveali...

Specific anionic residues of the recombinant kringle 2 domain of tissue-type plasminogen activator that are responsible for stabilization of its interaction with omega-amino acid ligands.

Biochemistry 32(14) , 3540-8, (1993)

The involvement of specific aspartic acid (D) and glutamic acid (E) residues of the recombinant (r) kringle 2 (K2) domain of tissue-type plasminogen activator (tPA) in stabilizing its interaction with omega-amino acid ligands has been assessed by examination ...

The cationic locus on the recombinant kringle 2 domain of tissue-type plasminogen activator that stabilizes its interaction with omega-amino acids.

Biochemistry 31(47) , 11698-706, (1992)

The properties of the cationic locus within the recombinant (r) kringle 2 domain (residues 180-261) of tissue-type plasminogen activator ([K2tPA]) that are responsible for stabilization of its interaction with the carboxylate moiety of omega-amino acid ligand...

Intravenous and oral administrations of DD2 [7-Amino-2-(sulfanylmethyl)heptanoic acid] produce thrombolysis through inhibition of plasma TAFIa in rats with tissue factor-induced microthrombosis.

Thromb. Res. 130(4) , e222-8, (2012)

Thrombin-activatable fibrinolysis inhibitor (TAFI) is a plasma zymogen that is activated by thrombin in plasma. In fibrinolytic processes, carboxy-terminal lysine (Lys) residues in partially degraded fibrin are important sites for plasminogen binding and acti...

Is there any need for a TAFI(a) inhibitor as thrombolytic drug?

Thromb. Res. 130(4) , 574-5, (2012)