4-(2-aminoethyl)benzene sulfonmide
4-(2-aminoethyl)benzene sulfonmide structure
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Common Name | 4-(2-aminoethyl)benzene sulfonmide | ||
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| CAS Number | 35303-76-5 | Molecular Weight | 200.258 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 387.4±44.0 °C at 760 mmHg | |
| Molecular Formula | C8H12N2O2S | Melting Point | 150-152 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 188.1±28.4 °C | |
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Multiple ligand detection and affinity measurement by ultrafiltration and mass spectrometry analysis applied to fragment mixture screening.
Anal. Chim. Acta 886 , 98-106, (2015) Binding affinity of a small molecule drug candidate to a therapeutically relevant biomolecular target is regarded the first determinant of the candidate's efficacy. Although the ultrafiltration-LC/MS (UF-LC/MS) assay enables efficient ligand discovery for a s... |
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Inhibition of hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II inhibitor-induced hepatocellular carcinoma cell apoptosis.
Acta Pharmacol. Sin. 32(7) , 912-20, (2011) The hypoxic condition within large or infiltrative hypovascular tumors produces intracellular acidification, which could activate many signaling pathways and augment cancer cell growth and invasion. Carbonic anhydrase-IX (CA-IX) is an enzyme lowering pH. This... |
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Probing protein binding spectra with Fourier microfluidics.
Conf. Proc. IEEE Eng. Med. Biol. Soc. 2010 , 5318-21, (2010) New developments in microfluidic chip technology enable the construction of chemical spectrum analyzers that can probe the binding interactions between chemical entities. In this paper we report the implementation of a microfluidic chip suitable for Fourier t... |
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Low noise detection of biomolecular interactions with signal-locking surface plasmon resonance.
Anal. Chem. 82(14) , 6025-31, (2010) Surface plasmon resonance (SPR) is a popular technique for label-free detection of biomolecular interactions at a surface. SPR yields quantitative kinetic association and dissociation constants of surface interactions such as the binding of two molecular spec... |
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Serine protease inhibitors block priming of monocytes for enhanced release of superoxide.
Immunology 86(4) , 629-35, (1995) Monocytes freshly isolated from human blood produced large amounts of superoxide when triggered by phorbol ester. After monocytes were cultured for 18-24 hr in endotoxin-free, non-adherent conditions, they produced low amounts of superoxide. Addition of lipop... |