Dynorphin A trifluoroacetate salt

Dynorphin A trifluoroacetate salt Structure
Dynorphin A trifluoroacetate salt structure
Common Name Dynorphin A trifluoroacetate salt
CAS Number 80448-90-4 Molecular Weight 2147.484
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C99H155N31O23 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Dynorphin A as a potential endogenous ligand for four members of the opioid receptor gene family.

J. Pharmacol. Exp. Ther. 286 , 136-141, (1998)

Dynorphin A is an endogenous opioid peptide that activates the kappa opioid receptor (KOR) with high potency. Some studies also showed that the distribution and functional activity of dynorphin A are not completely correlated with those of KOR, suggesting tha...

Structure-activity relationship studies of dynorphin A and related peptides.

Peptides 19 , 1277-1292, (1998)

An up-to-date review is presented covering all the available information concerning the isolation, discovery, synthesis, conformation, receptor binding characteristics, pharmacological properties and SAR studies of dynorphin A and related peptides. The potent...

The kappa opioid receptor and dynorphin co-localize in vasopressin magnocellular neurosecretory neurons in guinea-pig hypothalamus.

Neuroscience 96 , 373-383, (2000)

The relationship between the cloned kappa opioid receptor, dynorphin, and the neurohypophysial hormones vasopressin and oxytocin was analysed in the guinea-pig hypothalamic magnocellular neurosecretory neurons. This analysis was performed in order to understa...