methylthymol blue

methylthymol blue Structure
methylthymol blue structure
Common Name methylthymol blue
CAS Number 1945-77-3 Molecular Weight 756.816
Density 1.4±0.1 g/cm3 Boiling Point 891.6±65.0 °C at 760 mmHg
Molecular Formula C37H44N2O13S Melting Point N/A
MSDS USA Flash Point 493.0±34.3 °C

Polyamines in conventional and organic vegetables exposed to exogenous ethylene.

Food Chem. 188 , 218-24, (2015)

Relationships between endogenous levels of polyamines by thin layer chromatography (TLC) and gas chromatography (GC), nitrate and response to the application of ethylene were established between organic and conventional vegetables (broccoli, collard greens, c...

Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer.

Electrophoresis 35(24) , 3463-9, (2014)

Altered protein phosphorylation is a feature of many human cancers that can be targeted therapeutically. Phosphopeptide enrichment is a critical step for maximizing the depth of phosphoproteome coverage by MS, but remains challenging for tissue specimens beca...

MicroRNA signatures from multidrug‑resistant Mycobacterium tuberculosis.

Mol. Med. Report. 12 , 6561-7, (2015)

Tuberculosis (TB) infections, caused by multidrug‑resistant Mycobacterium tuberculosis (MDR MTB), remain a significant public health concern worldwide. The regulatory mechanisms underlying the emergence of MDR MTB strains remain to be fully elucidated, and fu...

Preclinical and Clinical Evidence of Mycobacterium tuberculosis Persistence in the Hypoxic Niche of Bone Marrow Mesenchymal Stem Cells after Therapy.

Am. J. Pathol. 185 , 1924-34, (2015)

Mycobacterium tuberculosis (MTB), the causative agent of pulmonary tuberculosis, is difficult to eliminate by antibiotic therapy. We recently identified CD271(+) bone marrow-mesenchymal stem cells (BM-MSCs) as a potential site of MTB persistence after therapy...

Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase.

FASEB J. 29 , 4804-14, (2015)

Pathogenic mycobacteria transport virulence factors across their complex cell wall via a type VII secretion system (T7SS)/early secreted antigenic target-6 of kDa secretion system (ESX). ESX conserved component (Ecc) B, a core component of the T7SS architectu...

What steps do we need to take to improve diagnosis of tuberculosis in children?

Expert Rev. Anti. Infect. Ther. 13 , 907-22, (2015)

Tuberculosis still represents a big global public health challenge. The diagnosis of tuberculosis and the differentiation between active and latent tuberculosis remain difficult, particularly in childhood, because of the lack of a gold standard test for diagn...

RD-1 encoded EspJ protein gets phosphorylated prior to affect the growth and intracellular survival of mycobacteria.

Sci. Rep. 5 , 12717, (2015)

Mycobacterium tuberculosis (MTB) synchronizes a number of processes and controls a series of events to subvert host defense mechanisms for the sake of residing inside macrophages. Besides these, MTB also possesses a wide range of signal enzyme systems, includ...

In silico-based high-throughput screen for discovery of novel combinations for tuberculosis treatment.

Antimicrob. Agents Chemother. 59 , 5664-74, (2015)

There are currently 18 drug classes for the treatment of tuberculosis, including those in the development pipeline. An in silico simulation enabled combing the innumerably large search space to derive multidrug combinations. Through the use of ordinary differ...

Immunomodulation in host-protective immune response against murine tuberculosis through regulation of the T regulatory cell function.

J. Leukoc. Biol. 98 , 827-36, (2015)

Tuberculosis, caused by the bacteria Mycobacterium tuberculosis, is characterized by an infection in lung and spleen. In the present study, we have elucidated the mechanism by which Mycobacterium indicus pranii renders protection in in vivo Mycobacterium tube...

CHO expressed recombinant human lactoferrin as an adjuvant for BCG.

Int. J. Immunopathol. Pharmacol. 28 , 452-68, (2015)

Lactoferrin (LF), an iron binding protein with immune modulatory activities, has adjuvant activity to enhance vaccine efficacy. Tuberculosis (TB) is a pulmonary disease caused by the pathogen Mycobacterium tuberculosis (MTB). Progressive TB disease is clinica...