γ-Cyclodextrin
γ-Cyclodextrin structure
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Common Name | γ-Cyclodextrin | ||
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| CAS Number | 17465-86-0 | Molecular Weight | 1297.125 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 845.2°C (rough estimate) | |
| Molecular Formula | C48H80O40 | Melting Point | 267ºC | |
| MSDS | Chinese USA | Flash Point | 450℃ | |
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Phthalimido-ferrocidiphenol cyclodextrin complexes: Characterization and anticancer activity.
Int. J. Pharm. 491 , 323-34, (2015) Several ferrocenyl analogues of tamoxifen have already showed strong antiproliferative activity in experimental glioma models. Nevertheless, these compounds are very poorly soluble in water and an adapted formulation is needed. In this work, we have tailored ... |
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Effect of γ-cyclodextrin on the in vitro skin permeation of a steroidal drug from nanoemulsions: impact of experimental setup.
Int. J. Pharm. 423(2) , 535-42, (2012) Numerous reports on the enhancement effect of cyclodextrins (CDs) on the skin permeation of dermally applied drugs exist, the majority of which is based on in vitro diffusion cell studies. The specific experimental setup of such studies may skew the obtained ... |
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Development of sucrose stearate-based nanoemulsions and optimisation through γ-cyclodextrin.
Eur. J. Pharm. Biopharm. 79(1) , 58-67, (2011) Nanoemulsions aimed at dermal drug delivery are usually stabilised by natural lecithins. However, lecithin has a high tendency towards self-aggregation and is prone to chemical degradation. Therefore, the aim of this study was to develop nanoemulsions with im... |
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Rhodamine B derivative-functionalized upconversion nanoparticles for FRET-based Fe(3+)-sensing.
Chem. Commun. (Camb.) 49(71) , 7797-9, (2013) A novel fluorescence resonance energy transfer (FRET)-based probe, γ-cyclodextrin modified oleic acid-NaYF4:Yb, Ho upconversion nanoparticles functionalized with a rhodamine B derivative (RBD), has been achieved for Fe(3+)-sensing in aqueous solution with hig... |
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Toxoplasma gondii in livestock in St. Kitts and Nevis, West Indies.
J. Phys. Chem. B 115(5) , 1268-74, (2011) Toxoplasma gondii is a ubiquitous protozoan parasite capable of infecting all warm-blooded animals including livestock. In these animals, the parasite forms cysts in the tissues which may pose a risk to public health if infected meat is consumed undercooked o... |
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Supramolecular hydrogels formed by pyrene-terminated poly(ethylene glycol) star polymers through inclusion complexation of pyrene dimers with γ-cyclodextrin.
Chem. Commun. (Camb.) 48(45) , 5638-40, (2012) Novel supramolecular hydrogels were formed between pyrene-terminated poly(ethylene glycol) star polymers and γ-cyclodextrin (γ-CD), through the inclusion complexation of dimers of the pyrene terminals with γ-CD, where γ-CD was directly used as a supramolecula... |
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Nanosponge formulations as oxygen delivery systems.
Int. J. Pharm. 402(1-2) , 254-7, (2010) Three types of cyclodextrin nanosponges were synthetized cross-linking α, β or γ cyclodextrin with carbonyldiimidazole as cross-linker. Nanosponges are solid nanoparticles previously used as drug carriers. In this studies cyclodextrin nanosponges were develop... |
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[Effect of different water-soluble forms of the fullerene C60 on the metabolic activity and ultra-structure of cells in culture].
Biofizika 57(3) , 468-75, (2012) In view of contradictory data on the toxicity of fullerenes for live organisms we studied the effect of water-soluble complexes of C60 with N-polyvivyl-pirrolidone (C60/PVP) and gamma-cyclodextrine (C60/gamma-CD) on MA-104 cells in culture. Both complexes pro... |
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[Effect of polymer carrier origin and physical state on fullerene C60 phototoxicity in vitro].
Eksp. Klin. Farmakol. 74(1) , 28-31, (2011) Biological effects of water-soluble inclusion complexes of fullerene C60 with poly(vinyl pyrrolidone) (C60/PVP) and gamma-cyclodextrin (C60/g-CD) as well as solid C60 (C60-coated surface) on cell viability have been studied in vitro. It is established that bo... |
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Stochastic modeling of flexible biomolecules applied to NMR relaxation. I. Internal dynamics of cyclodextrins: γ-cyclodextrin as a case study.
J. Phys. Chem. B 116(44) , 13159-71, (2012) In this work, we address the description of the dynamics of cyclodextrins in relation with nuclear magnetic resonance (NMR) relaxation data collected for hydroxymethyl groups. We define an integrated computational approach based on the definition and parametr... |