Drofenine hydrochloride

Drofenine hydrochloride Structure
Drofenine hydrochloride structure
Common Name Drofenine hydrochloride
CAS Number 548-66-3 Molecular Weight 353.92700
Density N/A Boiling Point 417.4ºC at 760mmHg
Molecular Formula C20H32ClNO2 Melting Point 145-147°
MSDS Chinese USA Flash Point 124.6ºC

Simultaneous determination of hydrochloride salts of adiphenine, diphenhydramine, ethyldiphenacetate, drofenine and promazine by ion-pair HPLC.

Boll. Chim. Farm. 122(8) , 405-11, (1983)

Functional and direct binding studies using subtype selective muscarinic receptor antagonists.

Br. J. Pharmacol. 93(3) , 491-500, (1988)

1. Muscarinic receptor antagonists were examined in direct binding studies on guinea-pig cardiac and cortical muscarinic receptors. Pirenzepine, dicyclomine and hexahydroadiphenine were shown to be selective ligands for the putative M1-muscarinic receptor. 2....

Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase.

Arch. Biochem. Biophys. 386(1) , 25-9, (2001)

Benactyzine and drofenine are widely used anticholinergic drugs. Benactyzine is used to treat organophosphate poisoning and drofenine acts on smooth muscle to stop muscle spasms. Both of these drugs are esters. After they enter the bloodstream, they will inte...