2,4-Dichloro-5-fluoro-3-nitrobenzoic acid

2,4-Dichloro-5-fluoro-3-nitrobenzoic acid Structure
2,4-Dichloro-5-fluoro-3-nitrobenzoic acid structure
Common Name 2,4-Dichloro-5-fluoro-3-nitrobenzoic acid
CAS Number 106809-14-7 Molecular Weight 253.999
Density 1.8±0.1 g/cm3 Boiling Point 390.4±42.0 °C at 760 mmHg
Molecular Formula C7H2Cl2FNO4 Melting Point 193-197 °C(lit.)
MSDS Chinese USA Flash Point 189.9±27.9 °C

Synthesis and antibacterial activity of some novel 4-oxopyrido[2,3-a]phenothiazines.

Arch. Pharm. (Weinheim) 347(11) , 861-72, (2014)

A series of substituted 4-oxopyrido[2,3-a]phenothiazine-3-carboxylic acids (6a-d) were prepared via cyclization of the corresponding ethyl 7-(arylthioxy)-8-nitro(or azido)-4-oxoquinoline-3-carboxylates (3a-d/4a-d), followed by hydrolysis of the resultant este...

Defluorinated sparfloxacin as a new photoproduct identified by liquid chromatography coupled with UV detection and tandem mass spectrometry.

Antimicrob. Agents Chemother. 42(5) , 1151-9, (1998)

Photodegradation of sparfloxacin was observed by means of high-pressure liquid chromatography with UV detection and liquid chromatography coupled with UV detection and tandem mass spectrometry (LC-MS/MS). Three products were detected. Comparison with an indep...

Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid, part VIII [1]. Convenient synthesis and antimicrobial properties of substituted hexahydro[1,4]diazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzodiazepine analog.

Molecules 13(11) , 2880-93, (2008)

[1,4]Diazepino[2,3-h]quinolone carboxylic acid 3 and its benzo-homolog tetrahydroquino[7,8-b]benzodiazepine-3-carboxylic acid 5 were prepared via PPAcatalyzed thermal lactamization of the respective 8-amino-7-substituted-1,4-dihydroquinoline-3-carboxylic acid...

Heterocycles [h]fused onto 4-oxoquinoline-3-carboxylic acid, part IV. Convenient synthesis of substituted hexahydro [1,4]thiazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzothiazepine homolog.

Molecules 12(8) , 1558-68, (2007)

Substituted [1,4]thiazepino[2,3-h]quinolinecarboxylic acid 3 is prepared by PPA-catalyzed thermal lactamization of the respective 8-amino-7-[(2-carboxyethyl)thio]-1,4-dihydroquinoline-3-carboxylic acid 9. The latter synthon is obtained by reduction of the 8-n...

Synthesis and antibacterial properties of new N4-acetylated hexahydro-2,7-dioxopyrido[2,3-f]quinoxaline-8-carboxylic acids.

J. Enzyme Inhib. Med. Chem. 26(5) , 649-56, (2011)

Direct interaction between 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid and primary α-amino acids (exemplified by glycine, alanine, and l-valine) in aqueous ethanolic NaHCO(3) at 70-80°C for 24-72 h produced the respect...

Synthesis and antibacterial activity of 9-cyclopropyl-4-fluoro-6-oxo-6, 9-dihydro-[1, 2, 5] thiadiazolo [3, 4-h] quinoline-7-carboxylic acid and its ethyl ester. Al-Qawasmeh RA, et al.

ARKIVOC 12 , 322-326, (2009)

Synthesis and antibacterial properties of new 8-nitrofluoroquinolone derivatives. Al-Hiari YM, et al.

Molecules 12(6) , 1240-1258, (2007)