1,2,4-Trimethoxybenzene

1,2,4-Trimethoxybenzene Structure
1,2,4-Trimethoxybenzene structure
Common Name 1,2,4-Trimethoxybenzene
CAS Number 135-77-3 Molecular Weight 168.190
Density 1.0±0.1 g/cm3 Boiling Point 247.0±0.0 °C at 760 mmHg
Molecular Formula C9H12O3 Melting Point 19 - 21ºC
MSDS Chinese USA Flash Point 77.9±19.1 °C

Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site.

Bioorg. Med. Chem. 19 , 1381-9, (2011)

Carbonic anhydrases (CAs, EC 4.2.1.1) are inhibited by sulfonamides, inorganic anions, phenols, coumarins (acting as prodrugs) and polyamines. A novel class of CA inhibitors (CAIs), interacting with the CA isozymes I, II (cytosolic) and IX, XII (transmembrane...