ubiquinone-9
ubiquinone-9 structure
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Common Name | ubiquinone-9 | ||
|---|---|---|---|---|
| CAS Number | 303-97-9 | Molecular Weight | 795.227 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 826.8±65.0 °C at 760 mmHg | |
| Molecular Formula | C54H82O4 | Melting Point | 41-43ºC | |
| MSDS | Chinese USA | Flash Point | 314.4±34.3 °C | |
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A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity.
Nat. Cell Biol. 17 , 782-92, (2015) The coordinated regulation of mitochondrial and nuclear activities is essential for cellular respiration and its disruption leads to mitochondrial dysfunction, a hallmark of ageing. Mitochondria communicate with nuclei through retrograde signalling pathways t... |
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Rapid high performance liquid chromatography-high resolution mass spectrometry methodology for multiple prenol lipids analysis in zebrafish embryos.
J. Chromatogr. A. 1412 , 59-66, (2015) The analysis of lipid molecules in living organism is an important step in deciphering metabolic pathways. Recently, the zebrafish has been adopted as a valuable animal model system to perform in vivo metabolomics studies, however limited methodologies and pr... |
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Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis.
Biochim. Biophys. Acta 1841(7) , 977-86, (2014) 2,3-Oxidosqualene is an intermediate in cholesterol biosynthesis and 2,3:22,23-dioxidosqualene act as the substrate for an alternative pathway that produces 24(S),25-epoxycholesterol which effects cholesterol homeostasis. In light of our previous findings con... |
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Determination of the coenzyme Q10 status in a large Caucasian study population.
Biofactors 41 , 211-21, (2015) Coenzyme Q10 (CoQ10 ) exists in a reduced (ubiquinol) and an oxidized (ubiquinone) form in all human tissues and functions, amongst others, in the respiratory chain, redox-cycles, and gene expression. As the status of CoQ10 is an important risk factor for sev... |
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Lipidomics reveals a remarkable diversity of lipids in human plasma.
J. Lipid Res. 51(11) , 3299-305, (2010) The focus of the present study was to define the human plasma lipidome and to establish novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid analysis is now a regular part of every patient's blood test and physicians r... |
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The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice.
J. Cell Biol. 199(2) , 215-24, (2012) Mclk1 (also known as Coq7) and Coq3 code for mitochondrial enzymes implicated in the biosynthetic pathway of ubiquinone (coenzyme Q or UQ). Mclk1(+/-) mice are long-lived but have dysfunctional mitochondria. This phenotype remains unexplained, as no changes i... |
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Aureimonas jatrophae sp. nov. and Aureimonas phyllosphaerae sp. nov., leaf-associated bacteria isolated from Jatropha curcas L.
Int. J. Syst. Evol. Microbiol. 63(Pt 5) , 1702-8, (2013) Four orange-pigmented isolates, L7-456, L7-484(T), L9-479 and L9-753(T), originating from surface-sterilized leaf tissues of Jatropha curcas L. cultivars were characterized using a polyphasic taxonomic approach. Phylogenetic analyses based on 16S rRNA gene se... |
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Association between serum level of ubiquinol and NT-proBNP, a marker for chronic heart failure, in healthy elderly subjects.
Biofactors 41(1) , 35-43, (2015) Ubiquinone and ubiquinol represent the oxidized and reduced forms of Coenzyme Q10 (CoQ10). CoQ10 is present in membranes of almost all human tissues and organs, with highest concentration in the heart. In patients with heart failure, serum levels of the N-ter... |
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A novel non-invasive sampling method using buccal mucosa cells for determination of coenzyme Q10.
Anal. Bioanal. Chem 407 , 5529-33, (2015) Coenzyme Q10 (CoQ10) is an important cofactor in the mitochondrial respiratory chain and a potent endogenous antioxidant. CoQ10 deficiency is often associated with numerous diseases, and patients can benefit from CoQ10 supplementation, being more effective wh... |
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Kistimonas scapharcae sp. nov., isolated from a dead ark clam (Scapharca broughtonii), and emended description of the genus Kistimonas.
Int. J. Syst. Evol. Microbiol. 62(Pt 12) , 2865-9, (2012) A Gram-negative, motile, facultatively anaerobic rod, designated A36(T), was isolated from a dead ark clam found on the south coast of Korea. The isolate was catalase- and oxidase-negative. 16S rRNA gene sequence analysis indicated that strain A36(T) was most... |