Josamycin
Josamycin structure
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Common Name | Josamycin | ||
|---|---|---|---|---|
| CAS Number | 16846-24-5 | Molecular Weight | 827.995 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 877.8±65.0 °C at 760 mmHg | |
| Molecular Formula | C42H69NO15 | Melting Point | 131.5℃ | |
| MSDS | Chinese USA | Flash Point | 484.7±34.3 °C | |
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Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli.
Antimicrob. Agents Chemother. 51 , 923-9, (2007) AcrAB-TolC is the major, constitutively expressed tripartite multidrug efflux system in Escherichia coli that recognizes various structurally unrelated molecules, including many antibiotics, dyes, and steroids. The AcrB inner membrane pump portion of the effl... |
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Performance characterization of a quantitative liquid chromatography-tandem mass spectrometric method for 12 macrolide and lincosamide antibiotics in salmon, shrimp and tilapia.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 203-10, (2014) This paper describes an extension and performance characterization of a quantitative confirmatory multi-residue liquid chromatography-tandem mass spectrometric method for residues of macrolide and lincosamide antibiotics, originally validated for application ... |
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Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.
J. AOAC Int. 98(1) , 230-47, (2015) Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using a validated LC-MS/MS method. There were two key points in s... |
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Ultra-high performance liquid chromatography-electrospray tandem mass spectrometry for the analysis of antibiotic residues in environmental waters.
Environ. Sci. Pollut. Res. Int. 22 , 16857-67, (2015) An optimized solid-phase extraction (SPE) and ultra-high performance liquid chromatography-electrospray tandem mass spectrometry (UPLC-MS/MS) method was developed for the effective analysis of 35 antibiotics including sulfonamides (SAs), quinolones (QLs), tet... |
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Occurrence and distribution of antibiotics in urban soil in Beijing and Shanghai, China.
Environ. Sci. Pollut. Res. Int. 22 , 11360-71, (2015) The recycling of reclaimed wastewater for irrigation and road cleaning is an important strategy to minimize water scarcity in megacities. However, little is known regarding the potential accumulation of antibiotics contained in reclaimed wastewater in urban s... |
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Occurrence, distribution and risks of antibiotics in urban surface water in Beijing, China.
Environ. Sci. Process. Impacts 17 , 1611-9, (2015) The occurrence and distribution of 22 antibiotics, including eight fluoroquinolones, nine sulfonamides and five macrolides, were investigated in the urban surface waters in Beijing, China. A total of 360 surface water samples were collected from the main rive... |
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Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk.
Food Chem. 171 , 98-107, (2014) Erythromycin is an antibiotic used extensively in veterinary practice worldwide for treatment, prevention and growth promotion. In this work, monoclonal antibodies (Mabs) against erythromycin were produced and used to develop a competitive indirect enzyme-lin... |
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Antimicrobial susceptibility and mechanisms of high-level macrolide resistance in clinical isolates of Moraxella nonliquefaciens.
J. Med. Microbiol. 63(Pt 2) , 242-7, (2014) We investigated antimicrobial susceptibility and the molecular mechanism involved in conferring high-level macrolide resistance in 47 clinical isolates of Moraxella nonliquefaciens from Japan. Antimicrobial susceptibility was determined using Etest and agar d... |
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[Detection and the antibiotic susceptibility analysis of mycoplasma and chlamydia in urogenital tract infections of 327 cases patients with tubal infertility].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 25(3) , 201-4, (2011) To explore the effects of mycoplasma and chlamydia infections on tubal infertilityand to assess the antibiotic susceptibility and resistance of female urogenital, and consequently to guide clinical rational drug use.327 tubal infertility women as infertility ... |
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Molecular mechanisms of macrolide resistance in clinical isolates of Mycoplasma pneumoniae from China.
Antimicrob. Agents Chemother. 53 , 2158-9, (2009) Fifty clinical Mycoplasma pneumoniae strains were isolated from 370 children with respiratory tract infections. Four strains were susceptible to macrolides, while the other 46 (92%) were macrolide resistant. The molecular mechanism of resistance was shown to ... |