1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine Structure
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine structure
Common Name 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
CAS Number 923-61-5 Molecular Weight 691.959
Density 1.01g/cm3 Boiling Point 723.6±70.0 °C at 760 mmHg
Molecular Formula C37H74NO8P Melting Point 197 °C
MSDS Chinese USA Flash Point 391.4±35.7 °C

The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.

Biochim. Biophys. Acta 1838(10) , 2615-24, (2014)

We have studied the dynamics of Lissamine Rhodamine B dye sensitization-induced oxidation of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) giant unilamellar vesicles (GUVs), where the progression of the underlying chemical processes was followed via vesicle...

Variations in pH sensitivity, acid stability, and fusogenicity of three influenza virus H3 subtypes.

J. Virol. 89(1) , 350-60, (2014)

Influenza A virus strains adapt to achieve successful entry into host species. Entry is mediated by the viral membrane protein hemagglutinin (HA), which triggers membrane fusion and genome release under acidic conditions in the endosome. In addition to change...

Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.

Biochim. Biophys. Acta 1828(9) , 2152-63, (2013)

Submillimolar concentrations of cytotoxic bile acids (BAs) induce cell death via apoptosis. On the other hand, several cytoprotective BAs were shown to prevent apoptosis in the same concentration range. Still, the mechanisms by which BAs trigger these opposit...

Evaluation of aegerolysins as novel tools to detect and visualize ceramide phosphoethanolamine, a major sphingolipid in invertebrates.

FASEB J. 29 , 3920-34, (2015)

Ceramide phosphoethanolamine (CPE), a sphingomyelin analog, is a major sphingolipid in invertebrates and parasites, whereas only trace amounts are present in mammalian cells. In this study, mushroom-derived proteins of the aegerolysin family—pleurotolysin A2 ...

Real-time intermembrane force measurements and imaging of lipid domain morphology during hemifusion.

Nat. Commun. 6 , 7238, (2015)

Membrane fusion is the core process in membrane trafficking and is essential for cellular transport of proteins and other biomacromolecules. During protein-mediated membrane fusion, membrane proteins are often excluded from the membrane-membrane contact, indi...

Biointerfacing polymeric microcapsules for in vivo near-infrared light-triggered drug release.

Nanoscale 7 , 19092-8, (2015)

Seeking safe and effective water-soluble drug carriers is of great significance in nanomedicine. To achieve this goal, we present a novel drug delivery system based on biointerfacing hollow polymeric microcapsules for effectively encapsulating water-soluble a...

Influence of lipid coatings on surface wettability characteristics of silicone hydrogels.

Langmuir 31(13) , 3820-8, (2015)

Insoluble lipids serve vital functions in our bodies and interact with biomedical devices, e.g., the tear film on a contact lens. Over a period of time, these naturally occurring lipids form interfacial coatings that modify the wettability characteristics of ...

Structure-dependent interactions of polyphenols with a biomimetic membrane system.

Biochim. Biophys. Acta 1838(10) , 2670-7, (2014)

Polyphenols are naturally-occurring compounds, reported to be biologically active, and through their interactions with cell membranes. Although association of the polyphenols with the bilayer has been reported, the detailed mechanism of interaction is not yet...

Membrane order parameters for interdigitated lipid bilayers measured via polarized total-internal-reflection fluorescence microscopy.

Biochim. Biophys. Acta 1838(11) , 2861-9, (2014)

Incorporating ethanol in lipid membranes leads to changes in bilayer structure, including the formation of an interdigitated phase. We have used polarized total-internal-reflection fluorescence microscopy (pTIRFM) to measure the order parameter for Texas Red ...

Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.

Sci. Rep. 5 , 16432, (2015)

A central tenet of signal transduction in eukaryotic cells is that extra-cellular ligands activate specific cell surface receptors, which orchestrate downstream responses. This ''protein-centric" view is increasingly challenged by evidence for the involvement...