3-Amino-4-cyanopyrazole

3-Amino-4-cyanopyrazole Structure
3-Amino-4-cyanopyrazole structure
Common Name 3-Amino-4-cyanopyrazole
CAS Number 16617-46-2 Molecular Weight 108.10
Density 1.4±0.1 g/cm3 Boiling Point 476.4±30.0 °C at 760 mmHg
Molecular Formula C4H4N4 Melting Point 172-174 °C(lit.)
MSDS Chinese USA Flash Point 241.9±24.6 °C

CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo.

Mol. Cell. Endocrinol. 393(1-2) , 56-64, (2014)

CLM29 (a pyrazolo[3,4-d]pyrimidine, that inhibits RET, epidermal growth factor receptor, vascular endothelial growth factor receptor, and has an anti-angiogenic activity) has anti-neoplastic activity in papillary dedifferentiated thyroid cancer. Here we teste...

Synlett , 65, (2006)

Helv. Chim. Acta 89 , 30, (2006)

Impurity profile study of zaleplon.

J. Pharm. Biomed. Anal. 44(1) , 101-9, (2007)

Zaleplon is a pyrazolopyrimidine derivative and possesses sedative and hypnotic properties. Seven unknown impurities in zaleplon bulk drug at levels below 0.1% were detected by reverse-phase high performance liquid chromatography (HPLC). The starting material...