1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE Structure
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure
Common Name 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS Number 17708-90-6 Molecular Weight 758.06000
Density N/A Boiling Point N/A
Molecular Formula C42H80NO8P Melting Point N/A
MSDS USA Flash Point N/A

Defective functionality of HDL particles in familial apoA-I deficiency: relevance of alterations in HDL lipidome and proteome.

J. Lipid Res. 55(12) , 2509-20, (2014)

To evaluate functional and compositional properties of HDL in subjects from a kindred of genetic apoA-I deficiency, two homozygotes and six heterozygotes, with a nonsense mutation at APOA1 codon -2, Q[-2]X, were recruited together with age- and sex-matched he...

Miscibility of Sphingomyelins and Phosphatidylcholines in Unsaturated Phosphatidylcholine Bilayers.

Biophys. J. 109 , 1907-16, (2015)

Polyunsaturated phospholipids are common in biological membranes and affect the lateral structure of bilayers. We have examined how saturated sphingomyelin (SM; palmitoyl and stearoyl SM (PSM and SSM, respectively)) and phosphatidylcholine (PC; dipalmitoyl PC...

Lipidomic analysis of human plasma reveals ether-linked lipids that are elevated in morbidly obese humans compared to lean.

Diabetol. Metab. Syndr. 5 , 24, (2013)

Lipidomic analysis was performed to explore differences in lipid profiles between plasma from lean and obese subjects, followed by in vitro methods to examine a role for the identified lipids in endothelial cell pathophysiology.Plasma was collected from 15 mo...

Human CD1-restricted T cell recognition of lipids from pollens.

J. Exp. Med. 202 , 295-308, (2005)

Plant pollens are an important source of environmental antigens that stimulate allergic responses. In addition to acting as vehicles for foreign protein antigens, they contain lipids that incorporate saturated and unsaturated fatty acids, which are necessary ...

DNA modification of live cell surface.

Nucleic Acids Res. 37 , e28, (2009)

We report a novel approach for the attachment of DNA fragments to the surface of live cells. By using fluorescence microscopy and flow cytometry we demonstrated that our synthetic conjugates of fatty acid with oligonucleotides can be incorporated in plasma me...

Hepatoprotectant ursodeoxycholyl lysophosphatidylethanolamide increasing phosphatidylcholine levels as a potential therapy of acute liver injury.

Front. Physiol. 3 , 24, (2012)

It has been long known that hepatic synthesis of phosphatidylcholine (PC) is depressed during acute such as carbon tetrachloride-induced liver injury. Anti-hepatotoxic properties of PC as liposomes have been recognized for treatment of acute liver damage. Urs...

Plasma HDL reduces nonesterified fatty acid hydroperoxides originating from oxidized LDL: a mechanism for its antioxidant ability.

Lipids 48 , 569-78, (2013)

The antioxidant property of plasma high-density lipoprotein (HDL) is thought to be involved in potential anti-atherogenic effects but the exact mechanism is not known. We aimed to reveal the contribution of HDL on the elimination of lipid hydroperoxides (LOOH...