EXODUS-2, MURINE
EXODUS-2, MURINE structure
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Common Name | EXODUS-2, MURINE | ||
|---|---|---|---|---|
| CAS Number | 196414-88-7 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10.
Mol. Cancer 2 , 22, (2004) SLC/CCL21, normally expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts T cells and dendritic cells (DC). We have previously shown that SLC/CCL21-mediated anti-tumor responses are accompanied by significant i... |
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Combination of SLC administration and Tregs depletion is an attractive strategy for targeting hepatocellular carcinoma.
Mol. Cancer 12 , 153, (2014) Secondary lymphoid tissue chemokine (SLC) is a key CC chemokine for chemotaxis of immune cells and has been an attractive candidate for anti-tumor treatments. However, among the immune cells recruited by SLC to tumors, the CD25+ Foxp3+ regulatory T cells (Tre... |
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Migratory properties of naive, effector, and memory CD8(+) T cells.
J. Exp. Med. 194 , 953-66, (2001) It has been proposed that two different antigen-experienced T cell subsets may be distinguishable by their preferential ability to home to lymphoid organs (central memory cells) or nonlymphoid tissues (effector memory/effector cells). We have shown recently t... |
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Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells.
J. Exp. Med. 197 , 643-56, (2003) Activated insulin-specific CD8(+) T cells (IS-CD8(+) cells) home to the pancreas, destroy beta cells, and cause rapid diabetes upon transfer into diabetes-prone NOD mice. Surprisingly, they also cause diabetes in mouse strains that are free of preexistent inf... |
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The anti-tumor effect and increased tregs infiltration mediated by rAAV-SLC vector.
Mol. Biol. Rep. 40 , 5615-23, (2013) To explore the anti-tumor effect and immune mechanism mediated by a new recombinant adeno-associated virus (rAAV) encoding secondary lymphoid tissue chemokine (SLC) mature peptide gene. AAV Helper-Free system was used for rAAV-SLC package. The anti-tumor effe... |