Theaflavine Gallate
Theaflavine Gallate structure
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Common Name | Theaflavine Gallate | ||
|---|---|---|---|---|
| CAS Number | 31629-79-5 | Molecular Weight | 716.598 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 1234.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C36H28O16 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 391.4±27.8 °C | |
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Black tea polyphenols inhibit tumor proteasome activity.
In Vivo 26(2) , 197-202, (2012) Tea is a widely consumed beverage and its constituent polyphenols have been associated with potential health benefits. Although black tea polyphenols have been reported to possess potent anticancer activities, the effect of its polyphenols, theaflavins on the... |
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The microbiota is essential for the generation of black tea theaflavins-derived metabolites.
PLoS ONE 7(12) , e51001, (2012) Theaflavins including theaflavin (TF), theaflavin-3-gallate (TF3G), theaflavin-3'-gallate (TF3'G), and theaflavin-3,3'-digallate (TFDG), are the most important bioactive polyphenols in black tea. Because of their poor systemic bioavailability, it is still unc... |
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Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant properties.
Basic Clin Pharmacol Toxicol. 103(1) , 66-74, (2008) This study compared the in vitro responses of human gingival fibroblasts and of carcinoma cells derived from the tongue to theaflavin-3-gallate (TF-2A) and theaflavin-3'-gallate (TF-2B), polyphenols in black tea. The antiproliferative and cytotoxic effects of... |
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Combination of HSCCC and Sephadex LH-20 methods An approach to isolation and purification of the main individual theaflavins from black tea.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 861(1) , 140-4, (2008) In order to separate the main individual theaflavin monomers from black tea, high-speed countercurrent chromatography (HSCCC) and Sephadex LH-20 column chromatography were applied. The results showed that theaflavin (TF1), theaflavin-3-gallate (TF2A), theafla... |
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PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate.
Eur. J. Pharmacol. 601(1-3) , 66-72, (2008) We have previously reported that black tea polyphenol theaflavin monogallate (TF-2) suppressed COX-2 and induced apoptosis in human colon cancer cells [Lu, J.B., Ho, C.-T., Ghai, G., Chen, K.Y., 2000. Differential effects of theaflavin monogallates on cell gr... |
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Characteristics of catechin- and theaflavin-mediated cardioprotection.
Exp. Biol. Med. (Maywood.) 233(4) , 427-33, (2008) Catechins and theaflavins-the main polyphenolic substances of green and black tea, respectively-exert a plethora of beneficial effects on the cardiovascular system. In a model of H(2)O(2)-mediated oxidative stress, we investigated the effects of epigallocatec... |
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Modulation of the oxidative stress and nuclear factor kappaB activation by theaflavin 3,3'-gallate in the rats exposed to cerebral ischemia-reperfusion.
Folia Biol. (Praha.) 53(5) , 164-72, (2007) The major pathobiological mechanisms of IR injury include excitotoxicity, oxidative stress, and inflammation. TF3, a major constituent of black tea, possesses biological functions such as anti-oxidative and anti-inflammatory activities. The purpose of this st... |
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Theaflavins extracted from black tea inhibit airway mucous hypersecretion induced by cigarette smoke in rats.
Inflammation 35(1) , 271-9, (2012) Theaflavins isolated from black tea have been used in studies on the prevention of tumor growth. The aim of this study was to investigate whether treatment with theaflavins influences the mucus hypersecretion induced by cigarette smoke in the lungs of experim... |
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Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate.
Carcinogenesis 20(4) , 733-6, (1999) Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells. In this... |
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alpha-Glucosidase inhibitory profile of catechins and theaflavins.
J. Agric. Food Chem. 55(1) , 99-105, (2007) To clarify the postprandial glucose suppression effect of flavonoids, the inhibitory effects of catechins and theaflavins against alpha-glucosidase (AGH) were examined in this study. It was initially demonstrated that theaflavins and catechins preferentially ... |