PQ1 Succinate
PQ1 Succinate structure
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Common Name | PQ1 Succinate | ||
|---|---|---|---|---|
| CAS Number | 955995-51-4 | Molecular Weight | 523.502 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H28F3N3O6 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Gap Junction Enhancer Potentiates Cytotoxicity of Cisplatin in Breast Cancer Cells.
J. Cancer Sci. Ther. 4(11) , 371-378, (2012) Cisplatin is one of the most widely used anti-cancer drugs due to its ability to damage DNA and induce apoptosis. However, increasing reports of side effects and drug resistance indicate the limitation of cisplatin in cancer therapeutics. Recent studies showe... |
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PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9.
Apoptosis 18(9) , 1071-82, (2013) Apoptosis, a programmed cell death, is an important control mechanism of cell homeostasis. Deficiency in apoptosis is one of the key features of cancer cells, allowing cells to escape from death. Activation of apoptotic signaling pathway has been a target of ... |
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The effect of the PQ1 anti-breast cancer agent on normal tissues.
Anticancer Drugs 23(9) , 897-905, (2012) Gap junctions are intercellular channels connecting adjacent cells, allowing cells to transport small molecules. The loss of gap junctional intercellular communication (GJIC) is one of the important hallmarks of cancer. Restoration of GJIC is related to the r... |