POLY(D-GLU, D-LYS) HYDROBROMIDE

POLY(D-GLU, D-LYS) HYDROBROMIDE Structure
POLY(D-GLU, D-LYS) HYDROBROMIDE structure
Common Name POLY(D-GLU, D-LYS) HYDROBROMIDE
CAS Number 119039-80-4 Molecular Weight 306.271
Density 1.5±0.1 g/cm3 Boiling Point 579.8±60.0 °C at 760 mmHg
Molecular Formula C13H12F2N6O Melting Point N/A
MSDS USA Flash Point 304.4±32.9 °C

Immunologic responses to conjugates of antigen E in patients with ragweed hay fever.

J. Allergy Clin. Immunol. 73 , 782-789, (1984)

Allergens conjugated with several simple repeating polymers have reduced allergenicity in man, but large doses retain the ability to suppress ongoing allergen-specific IgE synthesis in strains of high-responder mice. To determine whether suppression of IgE an...

Immunological tolerance to allergenic protein determinants: a therapeutic approach for selective inhibition of IgE antibody production.

Proc. Natl. Acad. Sci. U. S. A. 76 , 1430-1434, (1979)

Administration of stable conjugates prepared by coupling protein antigens such as ovalbumin or antigen E of ragweed extract to the synthetic random copolymer of D-glutamic acid and D-lysine (D-GL) is effective in inducing a state of long-lasting, antigen-spec...

Relation between optical configuration and immunogenicity of synthetic polypeptides.

Biochem. J. 96 , 577-582, (1965)

1. Three random linear copolymers composed of two or three of the amino acids d-tyrosine, d-glutamic acid, d-alanine and d-lysine, and a branched multichain copolymer with a poly-d-lysine backbone and polymeric side chains of d-tyrosine and d-glutamic acid, w...