Ambroxol HCl
Ambroxol HCl structure
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Common Name | Ambroxol HCl | ||
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| CAS Number | 23828-92-4 | Molecular Weight | 414.564 | |
| Density | N/A | Boiling Point | 468.6ºC at 760 mmHg | |
| Molecular Formula | C13H19Br2ClN2O | Melting Point | 235 - 240ºC | |
| MSDS | Chinese USA | Flash Point | 237.2ºC | |
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Gastro retention using polymer cocoons.
Artif. Cells. Nanomed. Biotechnol. 43(1) , 26-32, (2015) A gastro-retentive capsule has been prepared which is retained in the stomach for a period of 24h, providing a vehicle for the controlled delivery to the upper intestines. These "gastro cocoons" can resist passage through the sphincter of the stomach, and can... |
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Enzyme enhancers for the treatment of Fabry and Pompe disease.
Mol. Ther. 23(3) , 456-64, (2015) Lysosomal storage disorders (LSD) are a group of heterogeneous diseases caused by compromised enzyme function leading to multiple organ failure. Therapeutic approaches involve enzyme replacement (ERT), which is effective for a substantial fraction of patients... |
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Jauch, R., et al.
Arzneimittelforschung 13 , 474, (1963)
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Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
Neuropharmacology 49 , 1220, (2005) Neuropathic pain affects many patients, and treatment today is far from being perfect. Nav1.8 Na(+) channels, which are expressed by small fibre sensory neurons, are promising targets for novel analgesics. Na(+) channel blockers used today, however, show only... |