Buflomedil hydrochloride

Buflomedil hydrochloride Structure
Buflomedil hydrochloride structure
Common Name Buflomedil hydrochloride
CAS Number 35543-24-9 Molecular Weight 343.846
Density N/A Boiling Point 454.5ºC at 760 mmHg
Molecular Formula C17H26ClNO4 Melting Point 193°C
MSDS USA Flash Point 228.7ºC

Buflomedil: potential new indications for an old agent.

Int. Angiol. 28(3) , 170-4, (2009)

Our understanding of vascular pathophysiology has significantly improved during the past two decades. Patients with type 2 diabetes mellitus have an increased vascular risk and a series of modifiable risk factors play a crucial role in the atherosclerotic pro...

Vasoactive agent buflomedil up-regulated expression of vascular endothelial growth factor in a rat model of sciatic nerve crush injury.

Indian J. Pharmacol. 44(4) , 480-4, (2012)

To study the effect of Buflomedil on the morphological repair on crush injury of sciatic nerve and also the expression of vascular endothelial growth factor (VEGF).Rat sciatic nerves were crushed by pincers. All of the 400 Sprague Dawley rats were randomly di...

[Addition of antithrombosis in situ in the case of digital replantation: preliminary prospective study of 13 cases].

Chir. Main 29(5) , 326-31, (2010)

Antithrombotic agents are not routinely used in microsurgery for finger replantation. A prospective monocentric study of 13 cases of replantation at hand level is reported with local irrigation of anastomosis with urokinase and low-molecular-weight heparin. T...

[Multicentric study of thrombosis prevention in upper-extremity microsurgery. Survey at the Fesum centers].

Chir. Main 29(2) , 100-8, (2010)

Thrombosis is still the first cause of microsurgery failure. Lots of publications have been made but no consensus exists. We first analysed the results of our study in 53 French expert surgeons, then we compared them with the last published datas, most of all...

Effects of buflomedil on skin blood flow in patients with type 2 diabetes mellitus without overt micro- or macroangiopathy.

Int. Angiol. 30(2) , 164-71, (2011)

The aim of this study was to assess the effects of buflomedil on the peripheral microcirculation in patients with type 2 diabetes mellitus (T2DM) without overt micro- or macroangiopathy.Twenty-three patients with T2DM were randomly assigned to receive buflome...

[Long-term functional outcomes of digital ischemia under tourniquet: observations in three cases].

Chir. Main 31(6) , 358-63, (2012)

Digital tourniquet is a quick, simple and reliable method to ensure a bloodless operative field distal to the MP joint. However, a forgotten tourniquet is an exceptional but serious complication related to digital ischemia. Few cases were reported in literatu...

Safety of subcutaneous microinjections (mesotherapy) in musicians.

Med. Probl. Perform. Art. 26(2) , 79-83, (2011)

Determine the safety and tolerance of mesotherapy as a technique for the treatment of musculoskeletal complaints in musicians.67 patients (55.2% women) were subjected to a total of 267 mesotherapy sessions. A mesotherapy needle or normal needle was used rando...

A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite.

N. Engl. J. Med. 364(2) , 189-90, (2011)

Cutaneous granulomatous reaction from mesotherapy.

Dermatol. Surg. 35(2) , 291-3, (2009)

Letter by De Backer et al regarding article, "Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study".

Circulation 118(10) , e151, (2008)