Succinylmonocholine Chloride (125 mg)
Succinylmonocholine Chloride (125 mg) structure
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Common Name | Succinylmonocholine Chloride (125 mg) | ||
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| CAS Number | 5297-17-6 | Molecular Weight | 239.69700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H18ClNO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
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Chronotropic effects of succinylcholine and succinylmonocholine on the sinoatrial node.
Anesthesiology 57(4) , 289-92, (1982) The mechanism of bradycardia caused by the administration of succinylcholine has not been fully elucidated. Accordingly, the effects of succinylcholine and succinylmonocholine on the sinoatrial node were studied in 35 mongrel dogs. The sinus node artery was s... |
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A fully validated isotope dilution HPLC-MS/MS method for the simultaneous determination of succinylcholine and succinylmonocholine in serum and urine samples.
J. Mass Spectrom. 43(10) , 1344-52, (2008) A high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) method for the simultaneous detection of succinylcholine (SUX) and its metabolite succinylmonocholine (SMC) in serum and urine is presented. For interna... |
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Succinylmonocholine analytics as an example for selectivity problems in high-performance liquid chromatography/tandem mass spectrometry, and resulting implications for analytical toxicology.
Rapid Commun. Mass Spectrom. 22(12) , 1965-70, (2008) The determination and quantitation of drugs in biological matrices using high-performance liquid chromatography/tandem mass spectrometry (HPLC/MS/MS) is becoming increasingly popular in analytical toxicology, while at the same time a growing awareness for the... |
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Pharmacokinetic properties of succinylmonocholine in surgical patients.
J. Anal. Toxicol. 35(5) , 302-11, (2011) Intoxications with succinylcholine (SUX) lead to a potentially lethal respiratory paralysis, and forensic cases involving accidental or deliberate SUX-application have been reported. Detection of SUX as well as its metabolite succinylmonocholine (SMC) is diff... |
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Applicability of succinylmonocholine as a marker for succinylcholine administration--comparative analysis of samples from a fatal succinylcholine-intoxication versus postmortem control specimens.
Forensic Sci. Int. 207(1-3) , 84-90, (2011) Doubts concerning the applicability of succinylmonocholine (SMC) as a succinylcholine (SUX) marker have been issued. A comparative analysis of previously discussed tissues, i.e. brain, liver and kidney, was conducted to further elucidate this question by sear... |
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Degradation and elimination of succinylcholine and succinylmonocholine and definition of their respective detection windows in blood and urine for forensic purposes.
Int. J. Legal Med. 126(2) , 259-69, (2012) The muscle relaxant succinylcholine (SUX) evokes respiratory paralysis, and numerous cases of fatal SUX intoxication have been reported. Detection of SUX and its metabolite succinylmonocholine (SMC) is difficult, both due to their (bis-) quaternary structure ... |
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Comparison of the mode of action of succinylcholine and succinylmonocholine on rat skeletal muscle after denervation.
J. Pharm. Pharmacol. 39(3) , 173-9, (1987) The effects of equimolar concentrations (3.0 X 10(-5) M) of succinylcholine (SCh) and succinylmonocholine (SMC) were studied in-vitro at 20 degrees C in rat extensor digitorum longus muscle (EDL) 0-147 days after common peroneal nerve section. Analysis of sim... |
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Succinylmonocholine identified in negative control tissues.
J. Anal. Toxicol. 27(8) , 600-1, (2003)
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