Geranyl pyrophosphate lithium salt

Geranyl pyrophosphate lithium salt Structure
Geranyl pyrophosphate lithium salt structure
Common Name Geranyl pyrophosphate lithium salt
CAS Number 21141-43-5 Molecular Weight 332.01
Density N/A Boiling Point N/A
Molecular Formula C10H17Li3O7P2 Melting Point N/A
MSDS USA Flash Point N/A

Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species.

Phytochemistry 69(14) , 2539-45, (2008)

Natural rubber, cis-1,4-polyisoprene, is a vital industrial material synthesized by plants via a side branch of the isoprenoid pathway by the enzyme rubber transferase. While the specific structure of this enzyme is not yet defined, based on activity it is pr...

Muscular effects of statins in the elderly female: a review.

Clin. Interv. Aging 8 , 47-59, (2013)

Statins have demonstrated substantial benefits in supporting cardiovascular health. Older individuals are more likely to experience the well-known muscle-related side effects of statins compared with younger individuals. Elderly females may be especially vuln...

Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate.

Proc. Natl. Acad. Sci. U. S. A. 106(26) , 10865-70, (2009)

We identified a cis-prenyltransferase gene, neryl diphosphate synthase 1 (NDPS1), that is expressed in cultivated tomato (Solanum lycopersicum) cultivar M82 type VI glandular trichomes and encodes an enzyme that catalyzes the formation of neryl diphosphate fr...

GTPase stimulation in shrimp Ras(Q(61)K) with geranylgeranyl pyrophosphate but not mammalian GAP.

J. Exp. Zool. 290(6) , 642-51, (2001)

BALB/3T3 cells were transformed by transfection with DNA encoding the mutated ras(Q(61)K) from shrimp Penaeus japonicus (Huang et al., 2000). The GTPase-activating protein (GAP) in the cytosol fraction was significantly expressed and degraded, compared to unt...

Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay.

Assay Drug Dev. Technol. 5(2) , 205-14, (2007)

A mix-and-read FlashPlate (PerkinElmer, Waltham, MA) assay for the enzyme farnesyl pyrophosphate (FPP) synthase (FPPS) was developed to rapidly measure both steps in the synthesis of FPP from dimethylallyl pyrophosphate (DMAPP). The assay used either DMAPP or...

Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston].

BMC Mol. Biol. 11 , 88, (2010)

Geranyl pyrophosphate (GPP) and p-hydroxybenzoate (PHB) are the basic precursors involved in shikonins biosynthesis. GPP is derived from mevalonate (MVA) and/or 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway(s), depending upon the metabolite and the plant ...

Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase.

Neurosci. Lett. 354(2) , 107-10, (2004)

Statins were recently shown to possess anti-inflammatory activities, which might be responsible for their favourable effects in cardiovascular or CNS disorders independently from the inhibition of hydroxy-methyl-glutaryl CoA reductase. Here we investigated th...

[Current state of carotenoid biosynthesis in chloroplasts of eucaryotes].

Zh. Obshch. Biol. 63(4) , 299-325, (2002)

The author discusses the current state of biochemical and genetic aspects of carotenoid biosynthesis in chloroplasts of algae and higher plants. Two ways of biosynthesis of key C5-isoperene units have been considered: 1) from acetate (C2) via mevalonic acid (...

Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells.

Melanoma Res. 18(2) , 85-94, (2008)

Competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (the statins) that inhibit the synthesis of mevalonic acid are in wide use for treatment of hypercholesterolemia. Although antitumor effects on a variety of cell types have been reporte...

Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation.

Acta Crystallogr. D Biol. Crystallogr. 68(Pt 11) , 1558-69, (2012)

In the typical isoprenoid-biosynthesis pathway, condensation of the universal C(5)-unit precursors isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) occurs via the common intermediates prenyl pyrophosphates (C(10)-C(20)). The diversity o...