4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide
![4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide Structure](https://image.chemsrc.com/caspic/164/942296-25-5.png)
4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide structure
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Common Name | 4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide | ||
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| CAS Number | 942296-25-5 | Molecular Weight | 345.13 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H12INO3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones.
ACS Chem. Biol. 7(10) , 1719-28, (2012) Many bacterial pathogens use quorum sensing (QS) to control virulence. As a result, the development of methods to intercept QS has attracted significant interest as a potential anti-infective therapy. Acinetobacter baumannii has emerged as a pan-drug-resistan... |
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Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.
J. Am. Chem. Soc. 129(44) , 13613-25, (2007) Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. T... |
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Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes.
J. Am. Chem. Soc. 137(4) , 1510-9, (2015) The opportunistic pathogen Pseudomonas aeruginosa uses three interwoven quorum-sensing (QS) circuits-Las, Rhl, and Pqs-to regulate the global expression of myriad virulence-associated genes. Interception of these signaling networks with small molecules repres... |
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N-phenylacetanoyl-L-homoserine lactones can strongly antagonize or superagonize quorum sensing in Vibrio fischeri.
ACS Chem. Biol. 2(5) , 315-9, (2007) Bacteria monitor their population densities using low-molecular-weight ligands in a process known as quorum sensing. At sufficient cell densities, bacteria can change their mode of growth and behave as multicellular communities that play critical roles in bot... |