2-METHOXYACETOPHENONE

2-METHOXYACETOPHENONE Structure
2-METHOXYACETOPHENONE structure
Common Name 2-METHOXYACETOPHENONE
CAS Number 4079-52-1 Molecular Weight 150.174
Density 1.0±0.1 g/cm3 Boiling Point 237.9±0.0 °C at 760 mmHg
Molecular Formula C9H10O2 Melting Point 7-8 °C(lit.)
MSDS USA Flash Point 101.7±0.0 °C

Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells.

Drug Des. Devel. Ther. 9 , 349-417, (2015)

Plumbagin (PLB) has exhibited a potent anticancer effect in preclinical studies, but the molecular interactome remains elusive. This study aimed to compare the quantitative proteomic responses to PLB treatment in human prostate cancer PC-3 and DU145 cells usi...

Pharmacokinetics and pharmacodynamics of ticagrelor and prasugrel in healthy male Korean volunteers.

Clin. Ther. 37(3) , 563-73, (2015)

A combination of clopidogrel and aspirin is the standard treatment for patients with acute coronary syndrome and those undergoing percutaneous coronary intervention. Two novel antiplatelet agents, ticagrelor and prasugrel, have been shown to rapidly and more ...

Carboxylesterase 1-mediated drug-drug interactions between clopidogrel and simvastatin.

Biol. Pharm. Bull. 38(2) , 292-7, (2015)

Patients with coronary artery disease often receive concurrent treatment with clopidogrel and a hydroxymethylglutaryl (HMG)-CoA reductase inhibitor medication. Accordingly, potential drug-drug interactions associated with the concomitant use of these agents p...

The mitochondrial-targeted antioxidant MitoQ ameliorates metabolic syndrome features in obesogenic diet-fed rats better than Apocynin or Allopurinol.

Free Radic. Res. 48(10) , 1232-46, (2014)

The prevalence of metabolic syndrome (MetS) components including obesity, dyslipidemia, insulin resistance (IR), and hepatic steatosis is rapidly increasing in wealthy societies. It is accepted that inflammation/oxidative stress are involved in the initiation...

Interleukin-10 does not modulate clopidogrel platelet response in mice.

J. Thromb. Haemost. 14 , 596-605, (2016)

ESSENTIALS: It is unclear whether interleukin-10 (IL-10) could affect clopidogrel metabolism and response. The bioactivation of and response to clopidogrel were determined between mice with or without IL-10. Maximum clopidogrel active metabolite levels were t...