N-(2-Bromoethyl)phthalimide

N-(2-Bromoethyl)phthalimide Structure
N-(2-Bromoethyl)phthalimide structure
Common Name N-(2-Bromoethyl)phthalimide
CAS Number 574-98-1 Molecular Weight 254.080
Density 1.7±0.1 g/cm3 Boiling Point 342.9±25.0 °C at 760 mmHg
Molecular Formula C10H8BrNO2 Melting Point 80-83 °C(lit.)
MSDS Chinese USA Flash Point 161.2±23.2 °C

Identification and characterization of novel sirtuin inhibitor scaffolds.

Bioorg. Med. Chem. 17 , 7031-41, (2009)

The sirtuin proteins are broadly conserved NAD(+)-dependent deacetylases that are implicated in diverse biological processes including DNA recombination and repair, transcriptional silencing, longevity, apoptosis, axonal protection, insulin signaling, and fat...