8-Azidoadenosine 3':5'-cyclic monophosphate
8-Azidoadenosine 3':5'-cyclic monophosphate structure
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Common Name | 8-Azidoadenosine 3':5'-cyclic monophosphate | ||
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| CAS Number | 31966-52-6 | Molecular Weight | 370.21800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H11N8O6P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
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The covalent labeling of proteins by 17 beta-estradiol, retinoic acid, and progesterone in the human breast cancer cell lines MCF-7 and MCF-7/AdrR.
J. Steroid Biochem. Mol. Biol. 43(6) , 489-97, (1992) In this study we analyzed the covalent binding to proteins of 17 beta-estradiol (E2), retinoic acid (RA), and progesterone in MCF-7 and MCF-7/AdrR cells. MCF-7 cells have receptors for E2 and progesterone. MCF-7/AdrR cells do not have these receptors. After a... |
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A highly decreased binding of cyclic adenosine monophosphate to protein kinase A in erythrocyte membranes is specific for active psoriasis.
J. Invest. Dermatol. 119(1) , 160-5, (2002) A cyclic adenosine monophosphate binding abnormality in psoriatic erythrocytes that could be corrected by retinoid treatment has been reported. It was tested whether this binding abnormality is specific for psoriasis and the effects of treatment were compared... |
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Lipolytic membrane release of two phosphatidylinositol-anchored cAMP receptor proteins in yeast alters their ligand-binding parameters.
Arch. Biochem. Biophys. 308(2) , 504-14, (1994) Two new cAMP-binding proteins have been discovered recently in Saccharomyces cerevisiae. They are genetically distinct from the regulatory subunit of cytoplasmic cAMP-dependent protein kinase A and are distinguished from the latter, in addition, by their anch... |
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Luteinization-associated changes in protein stability of the regulatory subunit of the type I cAMP-dependent protein kinase.
J. Biol. Chem. 267(20) , 14335-44, (1992) The purpose of this study was to determine how RI alpha, the R subunit of the type I cAMP-dependent protein kinase, is regulated in rabbit ovarian follicles in response to the preovulatory luteinizing hormone surge. When soluble extracts from rabbit preovulat... |
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Post-translational modifications of the regulatory subunits of cAMP-dependent protein kinases during G1/S progression.
C. R. Acad. Sci. III 324(1) , 23-31, (2001) During the G1/S transition of the cell cycle variations in the labelling by 8-N3-[32P]cAMP of the protein kinase A regulatory subunits RI and RII, used as a probe to monitor post-translational modifications that may regulate cAMP binding, were observed in syn... |
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Cyclic AMP-dependent protein kinase in rat mammary tissue: expression of catalytic and regulatory subunits throughout pregnancy and lactation.
Biochem. J. 301 ( Pt 3) , 807-12, (1994) 'Expressed' and 'total' activities of cyclic AMP-dependent protein kinase (PK-A) were measured in extracts of rat mammary tissue sampled throughout pregnancy and lactation. Expression of the genes encoding the catalytic subunit (C-subunit) isoforms C alpha an... |
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Compartmentation of the type I regulatory subunit of cAMP-dependent protein kinase in cardiac ventricular muscle.
Arch. Biochem. Biophys. 348(2) , 391-402, (1997) The species-dependent compartmentation of type I cAMP-dependent protein kinase (PKA I) and its dissociated regulatory subunit (RI) was examined in the heart by biochemical and immunohistochemical means. PKA I and RI were resolved from type II cAMP-dependent p... |
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Cyclic AMP-dependent protein kinase isoenzymes in human myeloid leukemia (HL60) and breast tumor (MCF-7) cells.
Arch. Biochem. Biophys. 392(1) , 137-44, (2001) Combinations of retinoic acid (RA) and cAMP mediate many biological responses in a large variety of cell types. While the basis for the apparent synergistic effects of RA and cAMP are not clearly defined, it is likely that activation of PKA by cAMP is involve... |
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Cyclic adenosine 3':5'-monophosphate-dependent protein kinase on the external surface of LS-174T human colon carcinoma cells.
Biochemistry 38(1) , 172-9, (1999) The analysis of purified plasma membranes and the surface of intact cells revealed the presence of cyclic adenosine 3':5'-monophosphate-(cAMP) dependent protein kinase (PKA) on the external surface of LS-174T human colon carcinoma cells. Photoaffinity labelin... |
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Type I A-kinase is activated by platelet-derived growth factor in mesangial cells.
Biochem. Biophys. Res. Commun. 220(3) , 692-6, (1996) In the glomerular mesangial cell, platelet-derived growth factor (PDGF) activates several signal transduction pathways. We examined the effect of PDGF on cAMP production and on cAMP-dependent protein kinase (A-kinase) activation. In mesangial cells, PDGF stim... |