Hydrin 1

Hydrin 1 Structure
Hydrin 1 structure
Common Name Hydrin 1
CAS Number 122842-47-1 Molecular Weight 1392.61000
Density 1.57 g/cm3 Boiling Point N/A
Molecular Formula C57H93N21O16S2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Hydrins, hydroosmotic neurohypophysial peptides: osmoregulatory adaptation in amphibians through vasotocin precursor processing.

Proc. Natl. Acad. Sci. U. S. A. 86 , 5272-5275, (1989)

From neurointermediate pituitary glands of Xenopus laevis and Rana esculenta, previously unreported peptides termed hydrins, active on water permeability of frog urinary bladder and frog skin (Brunn or "water-balance" effect), have been isolated and sequenced...

Correlation between aquaporin and water permeability in response to vasotocin, hydrin and {beta}-adrenergic effectors in the ventral pelvic skin of the tree frog Hyla japonica.

J. Exp. Biol. 213 , 288-294, (2010)

The ventral pelvic skin of the tree frog Hyla japonica expresses two kinds of arginine vasotocin (AVT)-stimulated aquaporins (AQP-h2 and AQP-h3), which affect the capacity of the frog's skin to absorb water. As such, it can be used as a model system for analy...

Molecular cloning of an anuran V(2) type [Arg(8)] vasotocin receptor and mesotocin receptor: functional characterization and tissue expression in the Japanese tree frog (Hyla japonica).

Gen. Comp. Endocrinol. 132 , 485-498, (2003)

In most amphibians, [Arg(8)] vasotocin (VT) has an antidiuretic effect that is coupled to the activation of adenylate cyclase. In contrast, mesotocin (MT) has a diuretic effect and acts via the inositol phosphate/calcium signaling pathway in amphibians. To fu...

The water-absorption region of ventral skin of several semiterrestrial and aquatic anuran amphibians identified by aquaporins.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 , R1150-1162, (2010)

Regions of specialization for water absorption across the skin of Bufonid and Ranid anurans were identified by immunohistochemistry and Western blot analysis, using antibodies raised against arginine vasotocin (AVT)-stimulated aquaporins (AQPs) that are speci...

Adaptive evolution of water homeostasis regulation in amphibians: vasotocin and hydrins.

Biol. Cell 89(5-6) , 283-91, (1997)

Volemia and osmolality homeostasis is ensured in vertebrates through neuroendocrine reflexes, involving an afferent neural branch from baro- and osmo-receptors to hypothalamus and an efferent endocrine branch from secretory neurons to target hydroosmotic cell...

Effects of central vasopressin administration to infant rats.

Eur. J. Pharmacol. 233(1) , 101-7, (1993)

The neurohypophyseal peptide hormone arginine-vasopressin functions as a neuropeptide in several brain areas in addition to its role as a posterior pituitary hormone. Several studies indicate that arginine-vasopressin and arginine-vasopressin receptors appear...

Distinct hydro-osmotic receptors for the neurohypophysial peptides vasotocin and hydrins in the frog Rana esculenta.

Neuropeptides 29(5) , 301-7, (1995)

The biological properties of vasotocin, hydrin 1 (vasotocinyl-Gly-Lys-Arg) and hydrin 2 (vasotocinyl-Gly), in particular the hydro-osmotic activities on the frog skin, the frog urinary bladder and the frog kidney, have been compared. Hydrins are as active or ...

The cardiovascular and renal effects of hydrins and arginine vasotocin in frogs.

Gen. Comp. Endocrinol. 91(1) , 1-7, (1993)

Cardiovascular and renal actions of hydrins and arginine vasotocin (AVT) in frogs (Rana tigrina and Rana catesbeiana) were examined in view of their relationships as precursor/prohormone-hormones in the anuran amphibian. In vitro hydrins and AVT respectively ...

A fluorescent analogue of hydrin 1: a new probe for vasotocin receptors.

Am. J. Physiol. 259(4 Pt 1) , E524-8, (1990)

Hydrin 1 is the biosynthetic precursor of vasotocin in Xenopus laevis. We have synthesized deamino and fluorescein analogues of hydrin 1 and characterized their physiological action in the urinary bladder of the toad, Bufo marinus. 1-Deamino-hydrin 1 (d-hydri...

An additional arginine-vasotocin-related peptide, vasotocinyl-Gly-Lys, in Xenopus neurohypophysis.

Biochim. Biophys. Acta 1176 , 143, (1993)

The neurohypophysis of Xenopus and that of Ranidae and Bufonidae contain hydrin 1 (vasotocinyl-Gly-Lys-Arg) and hydrin 2 (vasotocinyl-Gly), respectively. In order to test the aldosterone-releasing activity of arginine vasotocin (AVT) and hydrin 1, purificatio...