Dopexamine hydrochloride
Dopexamine hydrochloride structure
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Common Name | Dopexamine hydrochloride | ||
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| CAS Number | 86484-91-5 | Molecular Weight | 429.42400 | |
| Density | N/A | Boiling Point | 546.7ºC at 760 mmHg | |
| Molecular Formula | C22H34Cl2N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 115.1ºC | |
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The effect of fenoldopam and dopexamine on cytokine and endotoxin release following on-pump coronary artery bypass grafting: a prospective randomized double-blind trial.
Heart Surg. Forum 13(6) , E353-61, (2010) Surgical trauma, exposure to an external circuit, and reduced organ perfusion contribute to the systemic inflammatory response following cardiopulmonary bypass (CPB). Reduced splanchnic perfusion causes disruption of the gastrointestinal mucosal barrier and t... |
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Is dopexamine superior to dopamine in the treatment of multiple trauma patients—A prospective, double-blind, randomised study
Injury 41(5) , 499-505, (2010) Background The goal of this prospective, randomised, double-blind clinical trial study was to assess the effects of dopexamine hydrochloride on organ failure, inflammatory mediators and splanchnic oxygenation in blunt multiple trauma patients at high risk of ... |
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Hemodynamic effects of dobutamine and dopexamine after cardiopulmonary bypass in pediatric cardiac surgery.
Paediatr. Anaesth. 19(9) , 862-71, (2009) After surgical repair of congenital heart disease, inotropic support is sometimes necessary to wean from cardiopulmonary bypass. In pediatric cardiac surgery, dobutamine and dopamine are often used as inotropic support. Dopexamine is a synthetic catecholamine... |
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Dopexamine Test in septic shock with hyperlactatemia.
Ann. Fr. Anesth. Reanim. 29(11) , 759-64, (2010) To evaluate the 6 hours haemodynamic effects of dopexamine (DPX) infusion in septic shock patients with persistent hyperlactatemia treated with high dose of norepinephrine (NE).Preliminary, prospective, uncontrolled study.Twenty-one septic shock with NE>0.5 μ... |
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Comparison of systemic and renal effects of dopexamine and dopamine in norepinephrine-treated septic shock.
J. Cardiothorac. Vasc. Anesth. 20(2) , 173-8, (2006) Vasopressor-induced vasoconstriction may compromise renal and splanchnic blood flow in patients with septic shock, resulting in secondary organ failures. The authors compared the effects of the vasodilatatory agent dopexamine against renal-dose dopamine and p... |
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Inotropic therapy for cardiac low output syndrome: comparison of hemodynamic effects of dopamine/dobutamine versus dopamine/dopexamine.
Eur. J. Med. Res. 13(10) , 459-63, (2008) To examine the effects of a therapy with dopexamine/dopamine in comparison with a regimen of dobutamine/dopamine on the outcome of patients with profound cardiogenic shock.Twenty patients presenting with an acute cardiogenic shock assisted with mechanical ven... |
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Effects of dopexamine on regional blood flow and leukotriene production in multiple splanchnic sites in endotoxemic rats.
Hepatogastroenterology. 53(67) , 39-44, (2006) This work examines the effects of lipopolysaccharide (LPS) on splanchnic blood flow and tests the potential effect of dopexamine in preventing LPS-induced decrease in splanchnic blood flow, also analyzing its influence on regional leukotriene production.Male ... |
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The effects of dopexamine in bupivacaine and ropivacaine induced cardiotoxicity in isolated rat heart.
Saudi Med. J. 27(8) , 1194-8, (2006) To compare the inotropic and chronotropic effects of ropivacaine and bupivacaine in an isolated, spontaneously beating rat heart, and to determine the reversal effects of dopexamine on these effects.The study was conducted at the Department of Physiology, Med... |
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Inotropic therapy for cardiac low output syndrome: comparison of hemodynamic effects of dopamine/dobutamine versus dopamine/dopexamine.
Eur. J. Med. Res. 12(11) , 563-7, (2007) To examine the effects of a therapy with dopexamine/dopamine in comparison with a regimen of dobutamine/dopamine on the outcome of patients with profound cardiogenic shock.Twenty patients presenting with an acute cardiogenic shock assisted with mechanical ven... |
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Meta-analyses of the effects of dopexamine in major surgery: do all roads lead to Rome?
Anaesthesia 64(6) , 585-8, (2009)
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