4-Methylthio benzoic acid
4-Methylthio benzoic acid structure
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Common Name | 4-Methylthio benzoic acid | ||
|---|---|---|---|---|
| CAS Number | 13205-48-6 | Molecular Weight | 168.213 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 319.0±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H8O2S | Melting Point | 192-196 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 146.7±23.2 °C | |
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4-Methylthiobenzoic acid reduces cisplatin nephrotoxicity in rats without compromising anti-tumour activity.
Biochem. Pharmacol. 41(12) , 1997-2003, (1991) Administration of 4-methylthiobenzoic acid (MTBA) (100 mg/kg) strongly reduced cisplatin nephrotoxicity (7.5 mg/kg, 20 min after MTBA) in rats as determined by histopathology and blood urea nitrogen. Anti-tumour activity against a colonic adenocarcinoma, CC 5... |
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Preventive action of thioethers towards in vitro DNA binding and mutagenesis in E. coli K12 by alkylating agents.
Mutat. Res. 245(2) , 67-74, (1990) Thioethers are effective scavengers of electrophilic metabolites derived from the hepatocarcinogen N-hydroxy-2-acetylaminofluorene (van den Goorbergh et al., 1987). In this study 2 of these thioethers, 4-(methylthio)benzoic acid (MTB) and its methylester, met... |
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