4-Bromophenyl methyl sulfone

4-Bromophenyl methyl sulfone Structure
4-Bromophenyl methyl sulfone structure
Common Name 4-Bromophenyl methyl sulfone
CAS Number 3466-32-8 Molecular Weight 235.098
Density 1.6±0.1 g/cm3 Boiling Point 348.6±34.0 °C at 760 mmHg
Molecular Formula C7H7BrO2S Melting Point 103-107 °C(lit.)
MSDS Chinese USA Flash Point 164.6±25.7 °C

Cerebrovasodilatation through selective inhibition of the enzyme carbonic anhydrase. 3. 5-(Arylthio)-, 5-(arylsulfinyl)-, and 5-(arylsulfonyl)thiophene-2-sulfonamides.

J. Med. Chem. 24(8) , 959-64, (1981)

A series of 5-(arylthio)-, 5-(arylsulfinyl)-, and 5-(arylsulfonyl)thiophene-2-sulfonamides is described and anticonvulsant activities are listed for the compounds. In most cases, the sulfones had the highest activity and the sulfides the least. Sulfones with ...

Efficient green-light-emitting electrochemical cells based on ionic iridium complexes with sulfone-containing cyclometalating ligands.

Chemistry 19(26) , 8597-609, (2013)

A new approach to obtain green-emitting iridium(III) complexes is described. The synthetic approach consists of introducing a methylsulfone electron-withdrawing substituent into a 4-phenylpyrazole cyclometalating ligand in order to stabilize the highest-occup...

Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.

J. Med. Chem. 45(1) , 219-32, (2002)

A novel series of sulfone N-formylhydroxylamines (retrohydroxamates) have been investigated as matrix metalloproteinases (MMP) inhibitors. The substitution of the ether linkage of ABT-770 (5) with a sulfone group 13a led to a substantial increase in activity ...

Cooperativity and steric hindrance: important factors in the binding of a-cyclodextrin with para-substituted aryl alkyl sulfides, sulfoxides and sulfones. Davies DM and Deary ME.

J. Chem. Soc., Perkin Trans. II 7 , 1287-1294, (1995)