Tris(2-butoxyethyl) phosphate

Tris(2-butoxyethyl) phosphate Structure
Tris(2-butoxyethyl) phosphate structure
Common Name Tris(2-butoxyethyl) phosphate
CAS Number 78-51-3 Molecular Weight 398.472
Density 1.0±0.1 g/cm3 Boiling Point 413.9±0.0 °C at 760 mmHg
Molecular Formula C18H39O7P Melting Point -70°C
MSDS Chinese USA Flash Point 241.5±47.7 °C

Elucidating toxicological mechanisms of current flame retardants using a bacterial gene profiling assay.

Toxicol. In Vitro 29 , 2124-32, (2015)

Flame retardants are ubiquitously used chemicals that have been shown to contaminate environments. Toxicological data is largely limited, with little insight into their molecular modes of action that may give rise to their toxic phenotypes. Such insight would...

Organophosphate flame retardants and organosiloxanes in predatory freshwater fish from locations across Canada.

Environ. Pollut. 193 , 254-61, (2014)

Whole body homogenates of Lake Trout (Salvelinus namaycush) or Walleye (Sander vitreus) collected from Canadian lakes were screened for organophosphate flame retardant (OPFR) and organosiloxane compounds. Six OPFR and five siloxane compounds were detected abo...

Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake, China.

Environ. Toxicol. Chem. 31(7) , 1478-84, (2012)

The concentrations and distribution of seven organophosphate flame retardants and plasticizers (OPs) were investigated in 28 sediment samples collected from Taihu Lake. The analytes were ultrasonically extracted, enriched using solid-phase extraction, and det...

Estimation of tris(2-butoxyethyl) phosphate in biological fluids: novel intersubject variability in recovery from human serum.

J. Pharm. Sci. 73(12) , 1791-3, (1984)

Tris(2-butoxyethyl) phosphate (I), a plasticizer commonly found in evacuated blood collection tubes, displaces many basic drugs from their binding sites on serum proteins and causes them to redistribute from serum into red blood cells (i.e., artificially lowe...

In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors.

Toxicology 314(1) , 76-83, (2013)

Various organophosphate flame retardants (OPFRs) are widely used in building materials, textiles and electric appliances, and have been reported to cause indoor environmental pollution in houses and office buildings. In this study, using cell-based transactiv...

Occurrence of organophosphate esters in surface water and ground water in Germany.

J. Environ. Monit. 3(6) , 621-6, (2001)

The present investigation was carried out to quantify the three organophosphate esters, tributyl phosphate (TBP), tris(2-chloroethyl) phosphate(TCEP) and tris(2-butoxyethyl) phosphate(TBEP), in river, rain and ground water obtained from several locations in G...

Induction of electrophysiological and morphological changes in Sprague-Dawley rats fed tributoxyethyl phosphate.

J. Appl. Toxicol. 4(1) , 42-8, (1984)

The effects of a widely used trialkyl phosphate (TP), tributoxyethyl phosphate (TBOP), on the peripheral nervous system of Sprague-dawley (SD) rats were investigated. Male and female SD rats were administered this chemical by gavage over a period of 18 weeks ...

Altered drug-serum protein binding in the genetically obese Zucker rat.

J. Pharm. Sci. 74(8) , 837-40, (1985)

Drug-serum protein binding was evaluated in genetically obese Zucker rats, their lean littermates, and lean Sprague-Dawley rats. The free fraction (fp) of phenytoin was significantly higher in the obese rat (fp = 0.177) compared to its lean littermate (fp = 0...

The effect of the plasticizers TBEP (tris-(2-butoxyethyl)-phosphate) and DEHP (di-(2-ethylhexyl)-phthalate) on beta-adrenergic ligand binding to alpha 1-acid glycoprotein and mononuclear leukocytes.

Biochem. Pharmacol. 38(15) , 2551-7, (1989)

The plasticizers tris-(2-butoxyethyl)-phosphate (TBEP) and di-(2-ethylhexyl)-phthalate (DEHP) and the beta-adrenergic receptor-blockers [3H]-(-)-dihydroalprenolol ([3H]-(-)-DHA) and [3H]-(-)-CGP 12177 were tested for their ability to interact with beta-adrene...

Subchronic oral toxicity of tributoxyethyl phosphate in the Sprague-Dawley rat.

Arch. Environ. Health 40(1) , 12-7, (1985)

The effects of the widely used alkyl phosphate, tributoxyethyl phosphate (TBOP), were investigated in male and female Sprague-Dawley rats. This chemical was administered (low dose: 0.25 ml/kg X day; high dose: 0.50 ml/kg X day) by gavage once a day for 5 days...