Imperatorin
Imperatorin structure
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Common Name | Imperatorin | ||
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| CAS Number | 482-44-0 | Molecular Weight | 270.280 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 448.3±45.0 °C at 760 mmHg | |
| Molecular Formula | C16H14O4 | Melting Point | 98-100ºC | |
| MSDS | Chinese USA | Flash Point | 224.9±28.7 °C | |
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Simultaneous determination of imperatorin and its 2 metabolites in dog plasma by using liquid chromatography-tandem mass spectrometry.
J. Pharm. Biomed. Anal. 70 , 640-6, (2012) In this study, 2 metabolites of imperatorin, imperatorin hydroxylate (IMH) and imperatorin epoxide (IME), were identified for the first time in dog plasma. A sensitive, specific, and accurate high-performance liquid chromatography-tandem mass spectrometry (LC... |
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A potential calcium antagonist and its antihypertensive effects.
Fitoterapia 82(7) , 988-96, (2011) Imperatorin (Imp) as a hypotensive active ingredient, its hypotensive effect was evaluated in the SHRs, its calcium antagonism and affinity to L-type calcium channel was also confirmed. The results showed that the blood pressure was decreased in the SHRs trea... |
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F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales.
PLoS ONE 7(2) , e30114, (2012) Two classes of F(420)-dependent reductases (FDR-A and FDR-B) that can reduce aflatoxins and thereby degrade them have previously been isolated from Mycobacterium smegmatis. One class, the FDR-A enzymes, has up to 100 times more activity than the other. F(420)... |
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Main constituents from the seeds of Vietnamese Cnidium monnieri and cytotoxic activity.
Nat. Prod. Res. 26(22) , 2107-11, (2012) From the ethyl acetate extract of the seeds of Vietnamese Cnidium monnieri L., three coumarins, osthole (1), xanthotoxin (2), imperatorin (3) and a sterol, daucosterol (4) have been purified. Their structures were elucidated by spectroscopic analysis. Further... |
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[A new natural product from root of Angelica dahurica cv. Qibaizhi].
Zhongguo Zhong Yao Za Zhi 37(16) , 2400-7, (2012) To study the chemical constituents of the root of Angelica dahurica cv. Qibaizhi.The compounds were isolated and purified by the methods of solvent extraction and chromatographic technique, and their structures were identified on the basis of the analyses of ... |
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Simultaneous quantification of furanocoumarins from Aegle marmelos fruit pulp extract.
J. Chromatogr. Sci. 53 , 576-9, (2015) Aegle marmelos Correa (Rutaceae) is a prominent species in the Sub-Himalayan region, also found in central and south India, and has been widely used as remedy for diarrhea and dysentery. Unripe fruits show antiviral activity and prove to be a potent hypoglyce... |
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Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study.
Pharmacol. Rep. 62(6) , 1231-6, (2010) The aim of this study was to determine and compare the anticonvulsant activities of four natural furanocoumarins [bergapten (5-methoxypsoralen), imperatorin (8-isopentenyloxypsoralen), oxypeucedanin (5-epoxy-isopentenyloxypsoralen) and xanthotoxin (8-methoxyp... |
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[Inhibitory effect of imperatorin and isoimperatorin on activity of cytochrome P450 enzyme in human and rat liver microsomes].
Zhongguo Zhong Yao Za Zhi 38(8) , 1237-41, (2013) Imperatorin (IM) and isoimperatorin (ISOIM) are major active components of common herbal medicines from Umbelliferae plants, and widely used in clinic. This article studies the inhibitory effect of IM and ISOIM on the activity of cytochrome P450 (CYP) enzyme,... |
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[Determination of supermolecular inclusion constants of hydroxylpropyl-beta-cylcodextrin with imperatorin and isoimperatorin by phase solubility method].
Zhong Yao Cai 34(6) , 965-7, (2011) To study the supermolecular interaction between different concentrations of hydroxypropyl-beta-cyclodextrin (HP-beta-CD) and imperatorin (IM) and isoimperatorin (ISO) using phase solubility analysis.Different concentrations of hydroxypropyl-beta-cyclodextrin ... |
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[Determination of imperatorin and isoimperatorin in cosmetics by high performance liquid chromatography-tandem mass spectrometry].
Se Pu 29(5) , 454-7, (2011) A novel method for the simultaneous determination of imperatorin and isoimperatorin in cosmetics by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was developed. The imperatorin and isoimperatorin were extracted by methanol. The ... |