Phenazine methylsulfate

Phenazine methylsulfate Structure
Phenazine methylsulfate structure
Common Name Phenazine methylsulfate
CAS Number 299-11-6 Molecular Weight 306.337
Density N/A Boiling Point N/A
Molecular Formula C14H14N2O4S Melting Point 158-160 °C (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

Season-dependent effects of elevated temperature on stress biomarkers, energy metabolism and gamete development in mussels.

Mar. Environ. Res. 103 , 1-10, (2014)

In coastal areas, sessile species can be severely affected by thermal stress associated to climate change. Presently, the effect of elevated temperature on metabolic, cellular and tissue-level responses of mussels was determined to assess whether the response...

Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.

J. Nutr. Biochem. 25(12) , 1254-62, (2014)

The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been shown to enhance the effect of chemotherapeutic drugs in clinical studies in cancer patients and to induce apoptotic tumor cell death in vitro. Until now,...

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.

Pharm. Res. 32(5) , 1546-56, (2015)

To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide (penetratin), all 5(6)-carboxytetramethylrhodamine-labeled,...

Extraction optimization, characterization and antioxidant activity in vitro of polysaccharides from mulberry (Morus alba L.) leaves.

Carbohydr. Polym. 128 , 52-62, (2015)

Extraction optimization, characterization and antioxidant activity in vitro of polysaccharides from mulberry leaves (MLP) were investigated in the present study. The optimal extraction conditions with an extraction yield of 10.0 ± 0.5% for MLP were determined...

Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways.

Int. J. Oncol. 46(3) , 1007-17, (2015)

Lung cancer is the leading cause of cancer death worldwide. Recently, two plant-derived drugs triptolide (TP) and hydroxycamptothecin (HCPT) both have shown broad-spectrum anticancer activities. Our previous study documented that combination treatment with th...

Distinctive structural hallmarks and biological activities of the multiple cathelicidin antimicrobial peptides in a primitive teleost fish.

J. Immunol. 194 , 4974-87, (2015)

Cathelicidin antimicrobial peptides (CAMPs) represent a crucial component of the innate immune system in vertebrates. Although widely studied in mammals, little is known about the structure and function of fish CAMPs. Further to the previous findings, two mor...

Effects of cytomegalovirus infection in human neural precursor cells depend on their differentiation state.

J. Neurovirol. 21 , 346-57, (2015)

Cytomegalovirus (CMV) is the most common cause of congenital infection in developed countries and a major cause of neurological disability in children. Although CMV can affect multiple organs, the most important sequelae of intrauterine infection are related ...

Design and development of novel mitochondrial targeted nanocarriers, DQAsomes for curcumin inhalation.

Mol. Pharm. 11(7) , 2334-45, (2014)

Curcumin has potent antioxidant and anti-inflammatory properties but poor absorption following oral administration owing to its low aqueous solubility. Development of novel formulations to improve its in vivo efficacy is therefore challenging. In this study, ...

Resveratrol loaded gelatin nanoparticles synergistically inhibits cell cycle progression and constitutive NF-kappaB activation, and induces apoptosis in non-small cell lung cancer cells.

Biomed. Pharmacother. 70 , 274-82, (2015)

Previously, we reported that the prepared resveratrol (RSV) loaded gelatin nanoparticles (GNPs) possessed enhanced anticancer effect than free RSV in non-small cell lung carcinoma cells and Swiss albino mice. The present study aims to explore the relevant mec...

Chemical constituents and biological activities of Cirsium leucopsis, C. sipyleum, and C. eriophorum.

Z. Naturforsch., C, J. Biosci. 69(9-10) , 381-90, (2015)

Two endemic Cirsium species, C. leucopsis DC. and C. sipyleum O. Schwarz, and C. eriophorum (L.) Scop. growing in Turkey were investigated to establish their secondary metabolites, fatty acid compositions, and antioxidant and anticholinesterase potentials. Sp...