GM 6001
GM 6001 structure
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Common Name | GM 6001 | ||
|---|---|---|---|---|
| CAS Number | 142880-36-2 | Molecular Weight | 388.461 | |
| Density | 1.228±0.06 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H28N4O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids.
Biochemistry 31 , 7152, (1992) The hydroxamic acid HONHCOCH2CH(i-Bu)CO-L-Trp-NHMe, isomer 6A (GM 6001), inhibits human skin fibroblast collagenase with Ki of 0.4 nM using the synthetic thiol ester substrate Ac-Pro-Leu-Gly-SCH(i-Bu)CO-Leu-Gly-OEt at pH 6.5. The other isomer, 6B, which has t... |
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