Adipohydrazide
Adipohydrazide structure
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Common Name | Adipohydrazide | ||
|---|---|---|---|---|
| CAS Number | 1071-93-8 | Molecular Weight | 174.201 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 519.3±33.0 °C at 760 mmHg | |
| Molecular Formula | C6H14N4O2 | Melting Point | 180-182 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 267.9±25.4 °C | |
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Preparation and testing of a Haemophilus influenzae Type b/Hepatitis B surface antigen conjugate vaccine.
Vaccine 33(13) , 1614-9, (2015) The majority of conjugate vaccines focus on inducing an antibody response to the polysaccharide antigen and the carrier protein is present primarily to induce a T-cell dependent response. In this study conjugates consisting of poly(ribosylribitolphosphate) (P... |
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FUBP1: a new protagonist in splicing regulation of the DMD gene.
Nucleic Acids Res. 43(4) , 2378-89, (2015) We investigated the molecular mechanisms for in-frame skipping of DMD exon 39 caused by the nonsense c.5480T>A mutation in a patient with Becker muscular dystrophy. RNase-assisted pull down assay coupled with mass spectrometry revealed that the mutant RNA pro... |
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Substrate stress relaxation regulates cell spreading.
Nat. Commun. 6 , 6364, (2015) Studies of cellular mechanotransduction have converged upon the idea that cells sense extracellular matrix (ECM) elasticity by gauging resistance to the traction forces they exert on the ECM. However, these studies typically utilize purely elastic materials a... |
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Structural and functional insights into sclerostin-glycosaminoglycan interactions in bone.
Biomaterials 67 , 335-45, (2015) In order to improve bone defect regeneration, the development of new adaptive biomaterials and their functional and biological validation is warranted. Glycosaminoglycans (GAGs) are important extracellular matrix (ECM) components in bone and may display osteo... |
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Brazilian meningococcal C conjugate vaccine: Scaling up studies.
Vaccine 33 , 4281-7, (2015) Several outbreaks caused by Neisseria meningitidis group C have been occurred in different regions of Brazil. A conjugate vaccine for Neisseria meningitidis was produced by chemical linkage between periodate-oxidized meningococcal C polysaccharide and hydrazi... |
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Co-delivery of hydrophobic paclitaxel and hydrophilic AURKA specific siRNA by redox-sensitive micelles for effective treatment of breast cancer.
Biomaterials 61 , 10-25, (2015) In this study, a novel redox-sensitive micellar system constructed from a hyaluronic acid-based amphiphilic conjugate (HA-ss-(OA-g-bPEI), HSOP) was successfully developed for tumor-targeted co-delivery of paclitaxel (PTX) and AURKA specific siRNA (si-AURKA). ... |
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The experimental therapy on brain ischemia by improvement of local angiogenesis with tissue engineering in the mouse.
Cell. Transplant. 23 Suppl 1 , S83-95, (2014) Neural restoration has proven to be difficult after brain stroke, especially in its chronic stage. This is mainly due to the generation of an unpropitious niche in the injured area, including loss of vascular support but production of numerous inhibitors agai... |
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A bio-inspired, microchanneled hydrogel with controlled spacing of cell adhesion ligands regulates 3D spatial organization of cells and tissue.
Biomaterials 58 , 26-34, (2015) Bioactive hydrogels have been extensively studied as a platform for 3D cell culture and tissue regeneration. One of the key desired design parameters is the ability to control spatial organization of biomolecules and cells and subsequent tissue in a 3D matrix... |
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pH-sensitive controlled release of doxorubicin from polyelectrolyte multilayers.
Colloids Surf. B Biointerfaces 125 , 127-33, (2015) Controlled and stimulated release of small drug molecules from polyelectrolyte multilayers is still a challenge due to the limitations to incorporate and control the interactions between small molecules and multilayers. Herein we reported a facile method to f... |
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Interconnected hyaluronic acid derivative-based nanoparticles for anticancer drug delivery.
Colloids Surf. B Biointerfaces 121 , 380-7, (2014) Doxorubicin (DOX)-loaded nanoparticles (NPs) based on interconnected hyaluronic acid-ceramide (HACE) structure were fabricated and their anti-tumor efficacy was evaluated in vitro. Interconnected HACE was synthesized by cross-linking HACE with adipic acid dih... |