2-Cyano-4-nitroaniline

2-Cyano-4-nitroaniline Structure
2-Cyano-4-nitroaniline structure
Common Name 2-Cyano-4-nitroaniline
CAS Number 17420-30-3 Molecular Weight 163.133
Density 1.4±0.1 g/cm3 Boiling Point 383.2±32.0 °C at 760 mmHg
Molecular Formula C7H5N3O2 Melting Point 200-207 °C(lit.)
MSDS Chinese USA Flash Point 185.6±25.1 °C

Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti-inflammatory Agents against Lipopolysaccharide-induced Acute Lung Injury in Rats.

Chem. Biol. Drug Des. 85 , 672-84, (2015)

Quinazoline has been reported to exhibit multiple bioactivities. The aim of this study was to discover new quinazoline derivatives with preventive effect on lipopolysaccharide-induced acute lung injury via anti-inflammatory actions. Thirty-three 4-amino quina...

SERRS dyes. Part 3. Synthesis of reactive benzotriazole azo dyes for surface enhanced resonance Raman scattering.

Analyst 129(10) , 975-8, (2004)

A series of eleven specially designed benzotriazole monoazo dyes for use in surface enhanced resonance Raman scattering studies are reported. Unlike previous benzotriazole dyes produced for SERRS, these dyes have been synthesised to be trifunctional in nature...

Synthesis and biological evaluation of 3,5-diaminoindazoles as cyclin-dependent kinase inhibitors.

Bioorg. Med. Chem. Lett. 18(7) , 2292-5, (2008)

A novel series of 3,5-diaminoindazoles were prepared and found to be CDK inhibitors. Potent inhibitors against CDK1 and CDK2 were obtained by introduction of 1lambda(6)-isothiazolidine-1,1-dioxide at 5-position of indazole. Anti-proliferative activities of co...

4-Arylamino-6-nitroquinazolines: Synthesis and their activities against neglected disease leishmaniasis.

Eur. J. Med. Chem. 108 , 13-20, (2016)

4-Arylamino-6-nitroquinazolines (2-25) were synthesized and evaluated for their leishmanicidal activities against Leishmania major promastigotes in vitro with IC50 values = 1.87-61.48 μM. Among the twenty four synthetic derivatives, 4-[4'-(methylsulfanyl)phen...