2-Hydroxy acid
2-Hydroxy acid structure
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Common Name | 2-Hydroxy acid | ||
|---|---|---|---|---|
| CAS Number | 609-71-2 | Molecular Weight | 139.109 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 427.5±30.0 °C at 760 mmHg | |
| Molecular Formula | C6H5NO3 | Melting Point | 258-261 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 212.4±24.6 °C | |
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New possible chelating agents of clinical interest for iron(III): 2-hydroxynicotinic acid and 3-hydroxypicolinic acid. A thermodynamic study.
Ann. Chim. 91(9-10) , 595-603, (2001) The formation of complexes between iron(III) and two ligands of possible relevance to chelation therapy, 2-hydroxynicotinic acid and 3-hydroxypicolinic acid, in aqueous 0.6 m (Na)Cl at 25 degrees C, has been investigated by means of potentiometric titrations ... |
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Permeation of aromatic carboxylic acids across lipid bilayers: the pH-partition hypothesis revisited.
Biophys. J. 89(3) , 1802-11, (2005) According to the pH-partition hypothesis the charged species of organic compounds do not contribute to lipid bilayer permeation as they generally show negligible partitioning into n-octanol. With this assumption, membrane permeation is related to the molar fr... |
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Comparing the lipid membrane affinity and permeation of drug-like acids: the intriguing effects of cholesterol and charged lipids.
Pharm. Res. 24(8) , 1457-72, (2007) Lipid bilayers regulate the passage of solutes into and between cellular compartments. A general prerequisite for this passage is the partitioning of the solute into the bilayer. We investigated the relationship between bilayer partitioning and permeation of ... |
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Synthesis and biological activity of 2-hydroxynicotinoyl-serine-butyl esters related to antibiotic UK-3A.
Bioorg. Med. Chem. Lett. 20(14) , 4018-20, (2010) Novel 2-hydroxynicotinoyl-serine-butyl esters have been synthesized. Three-step reactions from L-serine by esterification with n-butanol, amidation with 2-hydroxynicotinic acid and esterification with the corresponding carboxylic acids gave AD-1, AD-2 and AD-... |