Dihydrorhodamine 123
Dihydrorhodamine 123 structure
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Common Name | Dihydrorhodamine 123 | ||
|---|---|---|---|---|
| CAS Number | 109244-58-8 | Molecular Weight | 346.379 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 526.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H18N2O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 222.4±26.4 °C | |
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A yeast model of the Parkinson's disease-associated protein Parkin.
Exp. Cell Res. 333(1) , 73-9, (2015) Mutations in Parkin, an E3 ubiquitin ligase, are associated to autosomal recessive Parkinson's disease (PD). Parkin has been mainly implicated, along with Pink1, in mitochondrial autophagy in response to stress. In this study, a yeast model was developed to a... |
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Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite.
Biochim. Biophys. Acta 1843(11) , 2645-61, (2014) Interferon-gamma (Ifnγ), a known immunomodulatory cytokine, regulates cell proliferation and survival. In this study, the mechanisms leading to the selective susceptibility of some tumor cells to Ifnγ were deciphered. Seven different mouse tumor cell lines te... |
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Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol.
Biotechnol. Bioeng. 112 , 2417-28, (2015) Plant polyphenols are known to have varying antimicrobial potencies, including direct antibacterial activity, synergism with antibiotics and suppression of bacterial virulence. We performed the in vitro oligomerization of resveratrol catalyzed by soybean pero... |
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The role of nitric oxide synthase in an early phase Cd-induced acute cytotoxicity in MCF-7 cells.
Biol. Trace Elem. Res. 164(1) , 130-8, (2015) Literature to date has confirmed that cadmium (Cd) can accomplish its toxic effects via the free radical-induced damage, but Cd itself cannot generate free radicals directly. Nitric oxide (NO) is a fundamental molecule that interplays with reactive oxygen spe... |
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Nicorandil prevents sirolimus-induced production of reactive oxygen species, endothelial dysfunction, and thrombus formation.
J. Pharmacol. Sci. 127(3) , 284-91, (2015) Sirolimus (SRL) is widely used to prevent restenosis after percutaneous coronary intervention. However, its beneficial effect is hampered by complications of thrombosis. Several studies imply that reactive oxygen species (ROS) play a critical role in endothel... |
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Ursolic acid induces autophagy in U87MG cells via ROS-dependent endoplasmic reticulum stress.
Chem. Biol. Interact. 218 , 28-41, (2014) Malignant gliomas are the most common primary brain tumors, and novel ways of treating gliomas are urgently needed. Ursolic acid (UA), a pentacyclic triterpenoid, has been reported to exhibit promising antitumor activity. Here, we evaluated the effects of UA ... |
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Resveratrol protects PC12 cells against OGD/ R-induced apoptosis via the mitochondrial-mediated signaling pathway.
Acta Biochim. Biophys. Sin. (Shanghai) 48 , 342-53, (2016) In this study, we investigated the neuroprotective potential of resveratrol against oxygen glucose deprivation/reoxygenation (OGD/R)-induced apoptotic damages in well-differentiated PC12 cells and the underlying mechanisms. Cells were incubated under normal c... |
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Acute cadmium administration to rats exerts both immunosuppressive and proinflammatory effects in spleen.
Toxicology 326 , 96-108, (2014) Conflicting data (both suppression and augmentation as well as lack of the effect) exist in respect to cadmium (Cd) and splenic T cell-based immune cell activity. Spleen is also the site of innate immune responses but impact of Cd on this type of immunity has... |
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Toxicity of oral cadmium intake: Impact on gut immunity.
Toxicol. Lett. 237 , 89-99, (2015) Gastrointestinal tract is one of the main targets of cadmium (Cd), an important food and drinking water contaminant. In the present study, the effect of subchronic (30 days) oral (in water) intake of 5ppm and 50ppm of cadmium on immune responses in the gut wa... |
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Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells.
Int. J. Mol. Med. 36 , 53-64, (2015) Sulforaphane, a natural isothiocyanate compound found in cruciferous vegetables, has been shown to exert cardioprotective effects during ischemic heart injury. However, the effects of sulforaphane on cardiotoxicity induced by doxorubicin are unknown. Thus, in... |