Oxytetracycline Dihydrate

Oxytetracycline Dihydrate Structure
Oxytetracycline Dihydrate structure
Common Name Oxytetracycline Dihydrate
CAS Number 6153-64-6 Molecular Weight 496.46500
Density N/A Boiling Point 845.6ºC at 760 mmHg
Molecular Formula C22H28N2O11 Melting Point 181-182 °C
MSDS Chinese USA Flash Point 465.2ºC

Experimental study of the impact of antimicrobial treatments on Campylobacter, Enterococcus and PCR-capillary electrophoresis single-strand conformation polymorphism profiles of the gut microbiota of chickens.

J. Med. Microbiol. 63(Pt 11) , 1552-60, (2014)

An experiment was conducted to compare the impact of antimicrobial treatments on the susceptibility of Campylobacter, Enterococcus faecium and Enterococcus faecalis, and on the diversity of broiler microbiota. Specific-pathogen-free chickens were first orally...

Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds.

J. AOAC Int. 95(4) , 1010-5, (2012)

A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed. Samples were extracted with Na2EDTA-McIlvaine buffer and furt...

Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

Angew. Chem. Int. Ed. Engl. 51(44) , 11136-40, (2012)

A very accommodating host: Three tetracycline biosynthetic pathways were overexpressed and manipulated in the heterologous host Streptomyces lividans K4-114. Through the inactivation of various genes and characterization of the resulting biosynthetic intermed...

Topical steroids for chronic wounds displaying abnormal inflammation.

Ann. R. Coll. Surg. Engl. 95(4) , 291-6, (2013)

Chronic, non-healing wounds are often characterised by an excessive, and detrimental, inflammatory response. We review our experience of using a combined topical steroid, antibiotic and antifungal preparation in the treatment of chronic wounds displaying abno...

The interaction of polysaccharide from Auricularia polytricha with quantum dots and the protection of plasmid DNA from damage.

Appl. Biochem. Biotechnol. 169(8) , 2263-72, (2013)

As a kind of folk medicine, edible mushrooms are known to be of medicinal characteristics, for example antitumor activity. However, the mechanism is not clear. In this study, the fluorescence (FL) spectroscopy was used to study the binding reactions of polysa...

Concentration and distribution of antibiotics in water-sediment system of Bosten Lake, Xinjiang.

Environ. Sci. Pollut. Res. Int. 22(3) , 1670-8, (2015)

This study investigated the residues of four sulfonamides, four quinolones, and four tetracyclines in surface water as well as surficial sediment samples, of Bosten Lake, in Xinjiang, China. The results showed the presence of 10 out of the 12 selected antibio...

Quantitative performance of liquid chromatography coupled to Q-Exactive high resolution mass spectrometry (HRMS) for the analysis of tetracyclines in a complex matrix.

Anal. Chim. Acta 853 , 415-24, (2014)

The presence of antibiotics in the environment is of increased interest and, as modern mass spectrometers become more efficient, we are increasingly aware of traces of pharmaceuticals appearing in a wide range of environmental and biological matrices. The Q-E...

The development and validation of a rapid method for the determination of antimicrobial agent residues in milk and meat using ultra performance liquid chromatography coupled to quadrupole--Orbitrap mass spectrometry.

J. Pharm. Biomed. Anal. 102 , 184-92, (2014)

A new multi-class method has been developed for the identification and quantification of the residues of 26 antibiotics from different classes (sulfonamides, macrolides, tetracyclines, penicillins, and quinolones) in milk and meat by ultra performance liquid ...

Association efficiency of three ionic forms of oxytetracycline to cationic and anionic oil-in-water nanoemulsions analyzed by diafiltration.

J. Pharm. Sci. 104(3) , 1141-52, (2015)

The association efficiency of oxytetracycline (OTC) to pharmaceutical available, ionic oil-in-water nanoemulsions is studied. Theoretical mathematical developments allowed us to differentiate by diafiltration (DF) between thermodynamically and kinetically con...

Isolation of Escherichia coli strains with AcrAB-TolC efflux pump-associated intermediate interpretation or resistance to fluoroquinolone, chloramphenicol and aminopenicillin from dogs admitted to a university veterinary hospital.

J. Vet. Med. Sci. 76(7) , 937-45, (2014)

Understanding the prevalence of antimicrobial-resistance and the relationship between emergence of resistant bacteria and clinical treatment can facilitate design of effective treatment strategies. We here examined antimicrobial susceptibilities of Escherichi...