2-Bromothiophene-5-Sulfonamide

2-Bromothiophene-5-Sulfonamide Structure
2-Bromothiophene-5-Sulfonamide structure
Common Name 2-Bromothiophene-5-Sulfonamide
CAS Number 53595-65-6 Molecular Weight 242.114
Density 2.0±0.1 g/cm3 Boiling Point 386.4±52.0 °C at 760 mmHg
Molecular Formula C4H4BrNO2S2 Melting Point 138-142 °C(lit.)
MSDS Chinese USA Flash Point 187.5±30.7 °C

Synthesis, Density Functional Theory (DFT), Urease Inhibition and Antimicrobial Activities of 5-Aryl Thiophenes Bearing Sulphonylacetamide Moieties.

Molecules 20 , 19914-28, (2015)

A variety of novel 5-aryl thiophenes 4a-g containing sulphonylacetamide (sulfacetamide) groups were synthesized in appreciable yields via Pd[0] Suzuki cross coupling reactions. The structures of these newly synthesized compounds were determined using spectral...

Cerebrovasodilatation through selective inhibition of the enzyme carbonic anhydrase. 3. 5-(Arylthio)-, 5-(arylsulfinyl)-, and 5-(arylsulfonyl)thiophene-2-sulfonamides.

J. Med. Chem. 24(8) , 959-64, (1981)

A series of 5-(arylthio)-, 5-(arylsulfinyl)-, and 5-(arylsulfonyl)thiophene-2-sulfonamides is described and anticonvulsant activities are listed for the compounds. In most cases, the sulfones had the highest activity and the sulfides the least. Sulfones with ...

Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives.

Bioorg. Med. Chem. Lett. 15(3) , 617-20, (2005)

The anti-proliferative activity of acylated heterocyclic sulfonamides is described in Vascular Endothelial Growth Factor-dependent Human Umbilical Vascular Endothelial Cells (VEGF-HUVEC) and in HCT116 tumor cells in a soft agar diffusion assay.

Development of an Acyl Sulfonamide Anti-Proliferative Agent, LY573636· Na†. Yates MH, et al.

Org. Process Res. Dev. 13(2) , 255-262, (2009)

A facile synthesis of new 5-aryl-thiophenes bearing sulfonamide moiety via Pd (0)-catalyzed Suzuki-Miyaura cross coupling reactions and 5-bromothiophene-2-acetamide: As potent urease inhibitor, antibacterial agent and hemolytically active compounds. Noreen M, et al.

J. Saudi Chem. Soc. , (2014)