win-62577
win-62577 structure
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Common Name | win-62577 | ||
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| CAS Number | 138091-43-7 | Molecular Weight | 437.57600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H31N3O | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Synthesis and substance P receptor binding activity of androstano[3,2-b]pyrimido[1,2-a]benzimidazoles.
J. Med. Chem. 35 , 374, (1992) Several heterosteroids containing a dihydroethisterone skeleton were prepared and shown to displace substance P in a receptor binding assay. Further biochemical (kinetic and Scatchard analyses) and pharmacological evaluation (substance P-induced plasma extrav... |
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Antagonists that demonstrate species differences in neurokinin-1 receptors.
Mol. Pharmacol. 41 , 772, (1992) 125I-Bolton-Hunter-substance P (125I-BH-SP) binding properties of three novel classes of neurokinin-1 (NK-1) receptor antagonists were investigated in tissues derived from humans, guinea pigs, and rats. 125I-BH-SP was shown to bind to a single class of bindin... |
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