Ac-Lys-Ome HCl
Ac-Lys-Ome HCl structure
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Common Name | Ac-Lys-Ome HCl | ||
|---|---|---|---|---|
| CAS Number | 20911-93-7 | Molecular Weight | 238.712 | |
| Density | N/A | Boiling Point | 354.6ºC at 760mmHg | |
| Molecular Formula | C9H19ClN2O3 | Melting Point | 108-114ºC(lit.) | |
| MSDS | USA | Flash Point | 168.2ºC | |
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DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts.
J. Am. Chem. Soc. 130(2) , 703-9, (2008) The reaction between N(alpha)-acetyllysine methyl ester (Lys) and 2'-deoxyguanosine (dGuo) was used to study structural aspects of DNA-protein cross-link (DPC) formation. The precise structure of DPCs depended on the nature of the oxidant and cross-linking re... |
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Antifibrinolytic activities of alpha-N-acetyl-L-lysine methyl ester, epsilon-aminocaproic acid, and tranexamic acid. Importance of kringle interactions and active site inhibition.
Arterioscler. Thromb. 12(6) , 708-16, (1992) alpha-N-acetyl-L-lysine methyl ester (NALME) is a lysine analogue that reportedly binds to low-affinity lysine binding sites in plasmin(ogen) and miniplasmin(ogen). In the studies presented here, we show that NALME has antifibrinolytic activity; however, unli... |
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Characterization of antibodies to advanced glycosylation end products on protein.
J. Immunol. Methods 140(1) , 119-25, (1991) Antibodies directed against advanced glycosylation end products (AGEs) formed during a Maillard reaction have been generated and characterized. Since protein-bound AGEs recognized by the antibodies were labile to acid hydrolysis, the antibodies were further c... |
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Transforming growth factor-beta is activated by plasmin and inhibits smooth muscle cell death in human saphenous vein.
J. Vasc. Res. 42(3) , 247-54, (2005) The effect of activation of endogenous transforming growth factor-beta (TGF-beta) on smooth muscle cell apoptosis was assessed in human saphenous vein.Segments of human saphenous vein, obtained at the time of bypass graft surgery, were cultured for 14 days. D... |
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Plasmin-mediated fibroblast growth factor-2 mobilisation supports smooth muscle cell proliferation in human saphenous vein.
J. Vasc. Res. 38(5) , 492-501, (2001) The focus of this study was identification of the contribution of the plasminogen activator-plasmin system to smooth muscle cell proliferation and migration in human saphenous vein. Segments of human saphenous vein were grown in organ culture for up to 14 day... |