Carboxy-PTIO potassium
Carboxy-PTIO potassium structure
|
Common Name | Carboxy-PTIO potassium | ||
|---|---|---|---|---|
| CAS Number | 148819-94-7 | Molecular Weight | 315.386 | |
| Density | N/A | Boiling Point | 456.3ºC at 760 mmHg | |
| Molecular Formula | C14H17KN2O4 | Melting Point | 141-143°C | |
| MSDS | USA | Flash Point | 229.7ºC | |
|
Molecules involve in the self-protection of neurons against glucose-oxygen-serum deprivation (GOSD)-induced cell damage.
Brain Res. Bull. 79 , 169-76, (2009) Molecules involved in self-protection of neurons against glucose/oxygen/serum deprivation (GOSD) were investigated. Trypan blue dye exclusion assay, Western blotting, ELISA, cytokine antibody array and chemical blocking assay were applied in the study. Result... |
|
|
Dietary supplementation with sodium nitrite can exert neuroprotective effects on global cerebral ischemia/reperfusion in mice.
J. Anesth. 29 , 609-17, (2015) Nitrite-derived NO protects against middle cerebral artery occlusion in mice. We developed a new mouse model of global cerebral ischemia and reperfusion (GCI/R) involving reversible occlusion of the major vessels from the aortic arch supplying the brain, and ... |
|
|
Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction.
Biochemistry 32 , 827, (1993) A labile inorganic free radical, nitric oxide (.NO), is produced by nitric oxide synthase from the substrate L-arginine in various cells and tissues. It acts as an endothelium-derived relaxing factor (EDRF) or as a neurotransmitter in vivo. We investigated th... |
|
|
Therapeutic effects of imidazolineoxyl N-oxide against endotoxin shock through its direct nitric oxide-scavenging activity.
Biochem. Biophys. Res. Commun. 202 , 923-930, (1994) We recently found a new class of nitric oxide (NO) antidote, i.e., 2-phenyl-4,4,5,5,-tetramethylimidazoline-1-oxyl-3-oxide derivatives (PTIOs). It has a potent inhibitory action against endothelium-derived relaxing factor. Here, we report the effect of a wate... |
|
|
UV-induced downregulation of the CDC25B protein in human cells.
FEBS Lett. 584 , 1199-204, (2010) The CDC25B phosphatase regulates the activation of CDK1-Cyclin B at the onset of mitosis, being a key target of the checkpoint pathways activated by cellular stress and DNA damage. Previous work has reported that checkpoint activation induces the sequestratio... |