MPPG

MPPG Structure
MPPG structure
Common Name MPPG
CAS Number 169209-65-8 Molecular Weight 245.16900
Density N/A Boiling Point N/A
Molecular Formula C9H12NO5P Melting Point N/A
MSDS Chinese USA Flash Point N/A

Blockade of the locomotor stimulant effects of amphetamine by group I, group II, and group III metabotropic glutamate receptor ligands in the rat nucleus accumbens: possible interactions with dopamine receptors.

Neuropharmacology 44 , 717-727, (2003)

Previous investigations have shown that mGlu receptors would be involved in the amphetamine-induced motor response. However, data are somewhat controversial across studies where methodological protocols vary. The aim of the present study was to determine the ...

Antagonism of the presumed presynaptic action of L-AP4 on GABAergic transmission in the ventrobasal thalamus by the novel mGluR antagonist MPPG.

Neuropharmacology 35 , 239-241, (1996)

The metabotropic glutamate receptor (mGluR) agonists CCG-I and L-AP4, acting at Group II and Group III mGluRs respectively, can reduce GABAergic synaptic inhibition on single neurones in the rat thalamus in vivo via a presumed presynaptic mechanism. The actio...

Down-regulation of mGluR8 in pilocarpine epileptic rats.

Synapse 47 , (2003)

Activation of presynaptic metabotropic glutamate receptors (mGluRs) leads to a powerful inhibition of glutamate release from many synaptic terminals throughout the CNS. mGluRs as autoreceptors are believed to provide a negative feedback system that prevents p...