1-Methylpiperidine

1-Methylpiperidine Structure
1-Methylpiperidine structure
Common Name 1-Methylpiperidine
CAS Number 9007-90-3 Molecular Weight 99.174
Density 0.8±0.1 g/cm3 Boiling Point 97.6±3.0 °C at 760 mmHg
Molecular Formula C6H13N Melting Point N/A
MSDS USA Flash Point 3.3±0.0 °C

Effect of anti-gliadin IgY antibody on epithelial intestinal integrity and inflammatory response induced by gliadin.

BMC Immunol. 16 , 41, (2015)

Pepsin-trypsin resistant gliadin (PT-gliadin) promotes intestinal tissue inflammation and increases paracellular permeability of immunogenic gliadin peptides into the lamina propria. This leads to the complications seen in the pathogenesis of celiac disease (...

The Effect of Plant Proteins Derived from Cereals and Legumes on Heme Iron Absorption.

Nutrients 7 , 8977-86, (2015)

The aim of this study is to determine the effect of proteins from cereals and legumes on heme iron (Fe) absorption. The absorption of heme Fe without its native globin was measured. Thirty adult females participated in two experimental studies (15 per study)....

Difficult diagnosis of celiac disease: diagnostic accuracy and utility of chromo-zoom endoscopy.

Gastrointest. Endosc. 77(2) , 233-40, (2013)

Chromo-zoom endoscopy has been demonstrated to be valuable in assessing the degree of intestinal villous atrophy in patients with suspected celiac disease.To evaluate the diagnostic accuracy of chromo-zoom endoscopy in patients with difficult diagnosis becaus...

Gliadin activates arginase pathway in RAW264.7 cells and in human monocytes.

Biochim. Biophys. Acta 1842(9) , 1364-71, (2014)

Celiac disease (CD) is an autoimmune enteropathy triggered in susceptible individuals by the ingestion of gliadin-containing grains. Recent studies have demonstrated that macrophages play a key role in the pathogenesis of CD through the release of inflammator...

Bifidobacteria inhibit the inflammatory response induced by gliadins in intestinal epithelial cells via modifications of toxic peptide generation during digestion.

J. Cell. Biochem. 109 , 801-7, (2010)

Celiac disease (CD) is a chronic enteropathy triggered by intake of gliadin, the toxic component of gluten. This study aims at evaluating the capacity of different Bifidobacterium strains to counteract the inflammatory effects of gliadin-derived peptides in i...

Ineffective degradation of immunogenic gluten epitopes by currently available digestive enzyme supplements.

PLoS ONE 10 , e0128065, (2015)

Due to the high proline content of gluten molecules, gastrointestinal proteases are unable to fully degrade them leaving large proline-rich gluten fragments intact, including an immunogenic 33-mer from α-gliadin and a 26-mer from γ-gliadin. These latter pepti...

Serum autoantibodies directed against transglutaminase-2 have a low avidity compared with alloantibodies against gliadin in coeliac disease.

Clin. Exp. Immunol. 177(1) , 86-93, (2014)

Coeliac disease is characterized by intolerance to gliadin and related gluten components present in wheat, barley and rye. Coeliac disease patients harbour antibodies directed against alloantigens such as gliadin, but also against the autoantigen transglutami...

Randomized Feeding Intervention in Infants at High Risk for Celiac Disease

N. Engl. J. Med. 371(14) , 1304-15, (2014)

Background A window of opportunity has been suggested for reducing the risk of celiac disease by introducing gluten to infants at 4 to 6 months of age.

Introduction of gluten, HLA status, and the risk of celiac disease in children.

N. Engl. J. Med. 371(14) , 1295-303, (2014)

The relationship between the risk of celiac disease and both the age at which gluten is introduced to a child's diet and a child's early dietary pattern is unclear.We randomly assigned 832 newborns who had a first-degree relative with celiac disease to the in...

Nature of pectin-protein-catechin interactions in model systems: pectin-protein-catechin interactions.

Food Sci. Technol. Int. 19(2) , 153-65, (2013)

Apple pectins, proteins and catechins were combined in model systems, and the resulting hazes were measured by spectrophotometric method, a zeta potential and particle size analyzer and Ostwald viscosimeter. The amount of hazes formed depends on the concentra...