trans,trans-dibenzalacetone
trans,trans-dibenzalacetone structure
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Common Name | trans,trans-dibenzalacetone | ||
|---|---|---|---|---|
| CAS Number | 35225-79-7 | Molecular Weight | 234.292 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 400.7±34.0 °C at 760 mmHg | |
| Molecular Formula | C17H14O | Melting Point | 107-113 °C | |
| MSDS | Chinese USA | Flash Point | 176.1±20.6 °C | |
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Study on the substituents' effects of a series of synthetic chalcones against the yeast Candida albicans.
Eur. J. Med. Chem. 42 , 87-92, (2007) A large series of chalcones were synthesized and studied for activity against Candida albicans. The SAR analysis showed that the antifungal activity was highly dependent on the substitution pattern of the aryl rings and correlated to a large extent with the a... |
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Synthesis and structure-affinity relationships of novel dibenzylideneacetone derivatives as probes for β-amyloid plaques.
J. Med. Chem. 54 , 2225, (2011) A new and extensive set of dibenzylideneacetone derivatives was synthesized and screened for affinity toward Aβ(1-42) aggregates. Structure-activity relationships revealed the binding of dibenzylideneacetones to be affected by various substituents. The introd... |
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Kiyomori A, et al.
Tetrahedron Lett. 1999 40(14) , 2657-2660
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Structure–activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues
Eur. J. Med. Chem. 43 , 1621-31, (2008) Inhibition of cytochrome P450 (CYP) is a major cause of drug–drug interactions. In this work, inhibitory potentials of 33 curcumin analogues, i.e. 2,6-dibenzylidenecyclohexanone (A series), 2,5-dibenzylidenecyclopentanone (B series) and 1,4-pentadiene-3-one (... |
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Dibenzylideneacetone analogues as novel Plasmodium falciparum inhibitors.
Bioorg. Med. Chem. Lett. 21 , 3034-6, (2011) A series of dibenzylideneacetones (A1-A12) and some of their pyrazolines (B1-B4) were synthesized and evaluated in vitro for blood stage antiplasmodial properties in Plasmodium falciparum culture using SYBR-green-I fluorescence assay. The compound (1E, 4E)-1,... |