![]() URIDINE 5'-TRIPHOSPHATE TRISODIUM SALT structure
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Common Name | URIDINE 5'-TRIPHOSPHATE TRISODIUM SALT | ||
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CAS Number | 116295-90-0 | Molecular Weight | 586.11700 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C9H16N2Na3O17P3 | Melting Point | >140ºC (dec.)(lit.) | |
MSDS | USA | Flash Point | >230 °F |
Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination.
Cell. Mol. Life Sci. 71(24) , 4895-910, (2014) Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big demand to facilitate the structure determination process t... |
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The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Nat. Commun. 6 , 6281, (2015) In asthma, airflow obstruction is thought to result primarily from inflammation-triggered airway smooth muscle (ASM) contraction. However, anti-inflammatory and smooth muscle-relaxing treatments are often temporary or ineffective. Overproduction of the mucin ... |
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RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.
Genetics 189 , 165-176, (2011) Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits. Recently, facilitated GDP/GTP exchange by non-GPCR GEFs, ... |
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Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.
J. Cell Biol. 191 , 367-381, (2010) A key requirement for Rab function in membrane trafficking is site-specific activation by GDP-GTP exchange factors (GEFs), but the majority of the 63 human Rabs have no known GEF. We have performed a systematic characterization of the 17 human DENN domain pro... |
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APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.
PLoS ONE 6 , e23676, (2011) Besides regulation of actin cytoskeleton-dependent functions, Rho GTPase pathways are essential to cell cycle progression and cell division. Rho, Rac and Cdc42 regulate G1 to S phase progression and are involved in cytokinesis. RhoA GDP/GTP cycling is require... |
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Ubiquitination in Rho signaling.
Curr. Top. Med. Chem 11(23) , 2879-2887, (2011) The Rho family small GTPases of the Ras superfamily play key roles in regulating diverse signaling pathways that control a myriad of fundamental cellular processes such as cytoskeletal dynamics, cell cycle progression, gene expression, cell polarity, migratio... |