2-Naphthalenemethanol,3-methoxy-

2-Naphthalenemethanol,3-methoxy- Structure
2-Naphthalenemethanol,3-methoxy- structure
Common Name 2-Naphthalenemethanol,3-methoxy-
CAS Number 39110-92-4 Molecular Weight 188.22200
Density 1.166g/cm3 Boiling Point 347.2ºC at 760 mmHg
Molecular Formula C12H12O2 Melting Point 70-74ºC(lit.)
MSDS USA Flash Point 163.1ºC

Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2.

J. Med. Chem. 51 , 4708, (2008)

We report a series of inhibitors of secreted phospholipases A2 (sPLA2s) based on substituted indoles, 6,7-benzoindoles, and indolizines derived from LY315920, a well-known indole-based sPLA2 inhibitor. Using the human group X sPLA2 crystal structure, we prepa...